Analysis of the expanding caries area mechanism by cigarette smoke exposure

吸烟对唾液量、变形链球菌的活性和生长及再钙化部分的组成没有影响。暴露于香烟烟雾暂时降低了唾液中淀粉酶和过氧化物酶的活性。吸烟后大鼠腮腺和颌下腺血管舒张、充血。唾液腺未见炎性细胞浸润。吸烟暴露组大鼠的龋面积明显增加。这些结果表明，吸烟改变了大鼠上颌磨牙的唾液成分，扩大了龋齿面积。

The exposure of cigarette smoke did not change amount of saliva, activity and growth of Streptococcus mutans and component of re-calcification part. The exposure of cigarette smoke temporarily decreased the Amylase and Peroxidase activity in saliva. In the cigarette smoke-exposed rats, vasodilation and hyperemia in the parotid grand and submandibular gland were observed by histological analysis. Inflammatory cells were not found infiltrating the salivary glands. The area of caries in the cigarette smoke exposure caries rats were significantly increasing compared with the caries rats.These results suggest that cigarette smoke exposure changes salivary component and expands caries area in the maxillary molars of rat.