Control of monomer unit sequences and creation of high-order structures by dynamic reorganization of polymers with amino acid structures

含有氨基酸的二胺单体与二硫化碳反应，然后与二卤化物单体缩聚，得到主链上带有二硫代氨基甲酸键的类多肽聚合物。对这些聚合物的光照射通过二硫代氨基甲酸酯诱导了动态主链交换。还考察了聚赖氨酸侧链引入的亚胺与低分子量醛的交换反应，观察到较快的亚胺-醛交换反应。

Reaction of amino-acid-containing diamine monomers with carbon disulfide and the following polycondensation of the products with dihalide monomers afforded the corresponding polypeptide-like polymers with dithiocarbamate bonds in their main chains. Photo-irradiation to these polymers induced dynamic main-chain exchange through dithiocarbamates. Exchange reaction of imines introduced at side chains of poly(L-lysine) with low-molecular-weight aldehydes was also examined, and relatively fast imine-aldehyde exchange was observed.