An alternative treatment for osteoporosis with DHNA.

本研究旨在证实dna对去卵巢小鼠（OVX）的抗骨质疏松作用。本研究使用雌性ICR OVX小鼠和雌性ICR假手术小鼠。OVX小鼠随机分为四组：dna组、维生素K2（VK）组、利塞膦酸酯（Ris）组和对照组。组织学及影像学分析显示OVX组行骨狭窄，骨髓腔宽。另一方面，DHNA组和Ris组的骨质疏松改变有所改善。脱氧核糖核酸对改善骨质疏松引起的骨量减少有一定作用，可能成为骨质疏松症的替代药物。

The aim of this study is to confirm the antiosteoporotic effect of DHNA in ovariectomized(OVX) mice. This study used female ICR OVX mice and female ICR sham operated mice. OVX mice were randomized into four groups : DHNA group, Vitamine K2(VK) group, Risedronate(Ris) group and control group. Histological and radiographical analysis showed that in the OVX group, the travecular bone was narrow and the bone marrow cavity was wide. On the other hand, these osteoporotic changes were improved in DHNA and Ris group. DHNA had some effects for improving bone mass reduction caused by osteoporosis and may become an alternative medicine for osteoporosis.