Metabolomics for elucidation of wine evaluation

代谢组学技术沿着化学计量学的应用，为研究红葡萄酒代谢组学与品质之间的关系提供了新的思路。超高效液相色谱-飞行时间质谱联用技术（UPLC-TOFMS）可实现高通量分析。使用该技术，研究了广泛的代谢产物。分析了一组红葡萄酒在瓶内储存期间的情况。采用正交偏最小二乘判别分析（OPLS-DA）对不同贮存时间的红葡萄酒进行判别。此外，在红葡萄酒中检测到的葡萄花色素苷和吡喃花色素苷被发现是瓶老化的重要标志。

Applications of metabolomics techniques along with chemometrics provide an understanding in the relationship between metabolome of red wine and its quality. Ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC-TOFMS) allowed a high-throughput analysis. Using this technique, a wide range of metabolites were investigated. A set of red wines during bottle storage was analyzed. Red wines with different storage time were discriminated through orthogonal partial least squares discriminate analysis (OPLS-DA). Furthermore, grape anthocyanins and pyranoanthocyanins detected in red wine were found to be significant markers to bottle aging.