Metabolomics for elucidation of wine evaluation

代谢组学技术和化学计量学的应用为了解红酒代谢组学与品质之间的关系提供了新的思路。超高效液相色谱联用飞行时间质谱（UPLC-TOFMS）实现了高通量分析。使用这种技术，广泛的代谢物进行了研究。对一组红葡萄酒在装瓶期间的贮藏情况进行了分析。采用正交偏最小二乘鉴别分析（OPLS-DA）对不同贮藏时间的红葡萄酒进行了鉴别。此外，红葡萄酒中葡萄花青素和吡喃花青素的检测是瓶中陈酿的重要标志。

Applications of metabolomics techniques along with chemometrics provide an understanding in the relationship between metabolome of red wine and its quality. Ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry (UPLC-TOFMS) allowed a high-throughput analysis. Using this technique, a wide range of metabolites were investigated. A set of red wines during bottle storage was analyzed. Red wines with different storage time were discriminated through orthogonal partial least squares discriminate analysis (OPLS-DA). Furthermore, grape anthocyanins and pyranoanthocyanins detected in red wine were found to be significant markers to bottle aging.