A pharmacist's strategic practical use in promotion of gene medical treatment

推进基因信息医学研究，广泛推广基因筛查治疗，是促进针对个体基因差异的医学治疗的重要途径。因此，在本研究中，我们清楚地看到，在维持一定剂量华法林的情况下，健全性体重或心力衰竭有很大的影响，并且在反流性食管炎的治疗中，使用PPI的药物治疗受到CYP2C19基因多态性的影响。此外，还成立了日本基因组药理学研究组，旨在传播基因信息的相关知识和实际使用方法，并对药剂师、医生、护士和神户市民进行了讲座。

For promotion of the medical treatment tailored to individual gene differences, it is important to advance the medical research on gene information and widely spread the genetic-screening therapy. So, in this research, it was shown clearly that the anamnestic weight or heart failure has big influence on a maintenance given dose of warfarin, and that in the reflux esophagitis therapy, the medical treatment with PPI has been affected by the gene polymorphism of CYP2C19. Furthermore, the Japanese genome pharmacology study group was established for the purpose of spreading the pertinent knowledge and the practical use method of gene information, andthe lecture meeting was held to the pharmacist, physician, nurse and the citizens of Kobe.