Control of Reaching by Remapping Visual Space Maps in the Frontal Eye Field

当球员伸手去接网球并击球时，球员会做出协调的眼睛和手的动作，以准确地击球，然后将伸手动作的结果可视化。我们检测了猴子在仅用眼睛、只用一只手、或眼睛和一只手一起触及目标的情况下弓状皮质中的神经元活动。不同效应器在REACH的启动和执行过程中，弓状回皮质的分裂起着不同的作用。特别是，深皮质区域包含在到达执行之前和期间或在到达运动的自我监控期间始终活跃的神经元，无论是眼睛、一只手还是两者都是用来到达的。神经元活动的特性表明，弓状皮质自始至终协调到达运动，因此充当使用任何效应器的到达行为的任务控制。

When a player reaches for and hits a tennis ball, the player makes coordinated eye and hand movements to hit the ball accurately and subsequently visualize the outcome of the reaching action. We examined the neuronal activity in the periarcuate cortex of monkeys while using their eyes only, one hand only, or eyes and one hand together to reach for a target. Divisions of the periarcuate cortex play differential roles in the initiation and execution of reaching by the different effectors. In particular, the deep cortical region contained neurons that were invariantly active before and during reaching execution or during self-monitoring of the reaching movements regardless of whether the eyes, a hand, or both were used for reaching. The properties of the neuronal activities suggest that the periarcuate cortex orchestrates reaching movements from start to finish, thus serving as mission control for reaching behavior using any effector.