Quantitative elucidation of change in fluorine associated with caries progression and inhibition

我们开发了一种新的氟定量测量方法，使用微型质子诱导x射线发射(pixe) /质子诱导伽马射线发射（PIGE）。通过这种测量方法，首次有可能捕捉到牙齿脱矿时氟的运动。此外，牙齿中的氟随着脱钙而释放，再次进入牙齿。结果表明，常规测量的氟在牙齿中的浓度可能既包含了不附着在牙齿上的氟，如CaF2，也包含了附着在牙齿上的氟。

We have developed a new fluorine quantitative measurement method using a micro-PIXE (Proton Induced X-ray Emission) / PIGE (Proton Induced Gamma-ray Emission). By using this measurement method, it has become possible for the first time to catch the movement of fluorine upon demineralization of tooth. Further, it was shown that the fluorine in the tooth released with decalcified was again taken into the tooth.The possibility that concentration value of fluorine in the tooth measured conventionally was contained both those not attached to the tooth, such as CaF2, and those attached to the tooth, has been shown.