Synthetc Study and Reuse of IonSupported Methyfoxdes for Swern daton wthout Unpleasant Odor

在二氯甲烷中，在三乙胺存在下，两种离子负载的甲基亚砜C_6和C_(10)和草酰氯对各种苄基和烯丙醇、伯醇和仲醇进行Swern氧化，然后对反应混合物进行简单的二乙醚萃取，分别得到相应的醛和酮，产率较高，纯度较高。类似地，在二氯甲烷中，在三乙胺存在下，用两个离子支载的甲基硫化物C_6和N-氯代丁二酰亚胺对各种苄基和烯丙醇、伯醇和仲醇进行Corey-Kim氧化，然后用简单的二乙醚萃取，分别得到相应的醛和酮，产率高，纯度高。这两种反应都没有产生任何难闻的气味。在Swern氧化反应中，离子支载的甲基硫化物可以高产率地回收，并可以再次氧化生成离子支载的甲基亚硫醚C6和C&lt；10&gt；，供在同一氧化中重复使用。在Corey-Kim氧化反应中，离子支载的甲基硫化物C6和C&lt；10&gt；被高产率地回收，也可以重复用于相同的氧化反应。

The Swern oxidation of various benzylic and allylic alcohols, primary alcohols, and secondary alcohols with two ion-supported methyl sulfoxides C_6and C_<10>, and oxalyl chloride in the presence of triethylamine in dichloromethane, followed by simple diethyl ether extraction of the reaction mixture, gave the corresponding aldehydes and ketones, respectively, in good yields with high purity. Similarly, the Corey-Kim oxidation of various benzylic and allylic alcohols, primary alcohols, and secondary alcohols with two ion -supported methyl sulfides C_6 and_<10>, andCN-chlorosuccinimide in the presence of triethylamine in dichloromethane, followed by simple diethyl ether extraction of the reaction mixture, furnished the corresponding aldehydes and ketones, respectively, in good yields with high purity. Both reactions did not produce any unpleasant odor at all. In the Swern oxidation, ion-supported methyl sulfides were recovered in high yields and could be re-oxidized to produce ion-supported methyl sulfoxides C6andC_<10>, for reuse in the same oxidation. In the Corey-Kim oxidation, ion-supported methyl sulfidesC_6 and C_<10> were recovered in high yields and could be also reused for the same oxidation.