Decoding the spatiotemporal control of DNA replication and repair

DNA复制是基因遗传的基本机制，对所有细胞生命都至关重要。该项目旨在让我们了解人类细胞如何在时间和空间上协调DNA复制机制，以准确地复制人类基因组。通过应用多种创新方法和聘请跨学科研究团队，该项目预计将产生解释人类基因组如何复制的新知识。这些知识有望产生高质量的研究出版物，并提供经济效益，例如解锁新的可能获得专利的DNA技术。

DNA replication is the fundamental mechanism of genetic inheritance and essential for all cellular life. This project aims to inform our understanding of how human cells coordinate the DNA replication machinery in time and space to accurately copy the human genome. By applying multiple innovative approaches and employing an interdisciplinary research team, this project is anticipated to generate new knowledge that explains how the human genome is replicated. This knowledge is expected to generate research publications of high quality and provide economic benefits, such as unlocking new potentially patentable DNA technologies.