Institutional Career Development Core

摘要 斯克里普斯转化科学研究所（STSI）的KL 2职业发展计划旨在提供全面的临床- 转化研究能力，以未来的生物医学领导者和研究人员规划的职业生涯在学术 机构，医疗保健系统，社区/公共卫生计划，生物技术行业和优先级设定状态 和联邦卫生机构。我们奋进提供一个模范，高度鼓舞人心的，创新的，和培育环境 年轻的临床研究人员学习和实践研究独立的技能，促进学者的成功 通过广泛的实验室和临床研究选择，从现实世界的经验，并刺激授课 作为多学科研究团队的一部分的参与式经验。我们项目的基本原理是 全新的临床转化研究机会，课程和参与式培训的学者在斯克里普斯 研究所（TSRI）和斯克里普斯健康（SH）在精准医学领域以前最低限度地提供， 斯克里普斯自STSI成立以来，这些领域包括基因组学、生物信息学和社区参与， 逐步扩大到包括重要的，新的STSI集中在数字医学，药物发现，数据科学， 和行为健康。在STSI的KL 2临床学者计划的支持下，创建了新的教育内容， 由我们的教师在临床试验设计，偏见的来源，生物统计学，计算生物学，研究在不同的 人口和公私伙伴关系。KL 2学者计划现在分享这种教育和研究培训 广泛贯穿TSRI的研究生院和博士后的机会，并在SH的临床培训计划，而 作为斯克里普斯研究和临床社区之间的合作桥梁。 KL 2学者计划的主要活动包括：1）通过密切合作提出，进行和报告原创研究 我们的参与教师之间的指导; 2）旨在提供临床翻译的补充课程 科学奖界定的能力;和3）参与式培训，提高科学交流的技能， 团队合作、领导力和学术界与工业界的合作。6个2-3年KL 2头寸持续得到支持， 临床转化研究硕士的选择，并邀请初级教师或 博士后临床实习生谁已经表现出强烈的事先承诺，在研究的职业生涯。KL 2计划 为学者提供多学科的导师团队，因为他们通过以下方式发展技能并找到研究利基： 独立研究，课程，申请试点或其他种子赠款，收集初步研究数据，以及 这份出版物将成为独立供资的基础。 下一个周期的目标包括继续扩大现有的研究培训领域， 内容和交付，增加社区参与和外部参与的参与性经验，以及增加多样性 通过新的研究和招聘合作伙伴关系，我们的计划。

Abstract Scripps Translational Science Institute’s (STSI) KL2 career development program aims to deliver comprehensive clinical- translational research competencies to future biomedical leaders and investigators planning careers within academic institutions, healthcare systems, community/public health programs, the biotechnology industry, and priority-setting state and federal health agencies. We endeavor to provide an exemplary, highly inspirational, innovative, and nurturing setting in which young clinician investigators learn and practice skills toward research independence, promoting scholar success through extensive laboratory and clinical research options, classes taught from real-world experience, and stimulating participatory experiences as part of multidisciplinary research teams. The rationale for our program has been to create entirely new clinical-translational research opportunities, coursework, and participatory training for scholars at The Scripps Research Institute (TSRI) and Scripps Health (SH) within precision medicine domains previously minimally available at Scripps. Since STSI’s inception, these domains have included genomics, bioinformatics, and community engagement, and have gradually expanded to include important, new STSI concentrations in digital medicine, drug discovery, data science, and behavioral health. Bolstered by STSI’s KL2 clinical scholars program, new educational content has been created and taught by our faculty in clinical trial design, sources of bias, biostatistics, computational biology, research in diverse populations, and public-private partnerships. The KL2 scholars program now shares this education and research training widely throughout TSRI’s Graduate School and postdoctoral opportunities and within SH’s clinical training programs, while functioning as a collaborative bridge between Scripps’ research and clinical communities. Key activities in the KL2 scholar program include: 1) proposing, conducting, and reporting original research through close mentorship among our participating faculty; 2) complementary coursework designed to deliver Clinical Translational Science Award-delineated competencies; and 3) participatory training that increases skills in scientific communication, teamwork, leadership, and academic-industry collaboration. Six, 2-3 year KL2 positions are supported continuously, with an option for a Master’s in Clinical-Translational Investigation, and applications are invited from junior faculty or from postdoctoral clinical trainees who have demonstrated a strong prior commitment to a career in research. The KL2 program provides multidisciplinary mentorship teams for scholars as they develop skills and find a research niche through independent studies, coursework, applications for pilot or other seed grants, collection of preliminary research data, and publication that will form the basis for independent funding. Objectives for the next cycle include continued expansion of the available research training domains, innovative educational content and delivery, increased participatory experiences in community engagement and externships, and increased diversity in our program through new research and recruitment partnerships.