National Pediatric Rehabilitation Resource Center: Mentored Collaborative Opportunities

项目摘要(有指导的协作机会) 我们提出了一系列有指导的协作机会，这些机会建立在我们团队的专业知识和独特的基础上 I)弗吉尼亚理工大学(位于罗阿诺克)与我们的神经运动研究诊所、我们的人类 神经成像实验室和我们新的治疗实施中心；ii)俄亥俄州立大学(哥伦布) 我们的珍珠实验室(儿科和康复实验室)提供复杂的生物力学(运动检测器) 和行为记录能力，我们的婴儿神经成像专业知识，我们的伤害预防和康复 研究实验室(IPARR)和我们新的神经运动评估中心；以及iii)全国儿童医院(In 哥伦布)，一直被评为最好的十大儿童医院，坚定地致力于发现和 从新生儿期到青春期的NIH儿科康复试验的活跃组合。这个 合作将建立在我们团队在重大科学会议上的演讲基础上，并计划采取后续行动 活动(见教学互动)，我们与小额赠款接受者的密切合作(见试点研究)，以及我们的 团队成员积极参与临床和翻译科学奖(CTSA)以及国家和 国际特别研究兴趣小组和NIH研究网络，最集中的是StrokeNet。 有指导的协作机会的具体目标是： 1)确定处于有利地位的个人和研究团队，以做出具有重大影响和新颖的贡献 儿科医学康复研究。我们寻求开发针对个人定制的指导协作，以 加强合作者的知识和研究技能的广度和深度；以及 2)提供集中的指导式协作体验，侧重于提高 研究人员及其在儿科康复研究中竞争性应用的质量。这些措施包括 教育和实践机会的组合，将支持第一阶段到第三阶段的临床试验， 比较有效性和以实践为基础的研究，重点方法研究和实施 科学试验。 我们将记录我们提供的所有有指导的协作机会，并及时征求用户的反馈 关于我国儿科康复资源中心支持的成效和影响 (PedRehab Ctr)我们保留适度的资金来帮助支付一些研究费用(例如，专门的材料 和旅行)，尽管家庭机构预计将为参与者提供大部分支持。

Project Summary (Mentored Collaborative Opportunities) We propose a range of Mentored Collaborative Opportunities that build on our team's expertise and distinctive research resources at i) Virginia Tech (in Roanoke) with our Neuromotor Research Clinic, our Human Neuroimaging Lab, and our new Treatment Implementation Center; ii) The Ohio State University (in Columbus) with our PeaRL Lab (Pediatric and Rehabilitation Lab) offering sophisticated biomechanical (motion detector) and behavioral recording capacity, our infant neuroimaging expertise, our Injury Prevention and Rehabilitation Research Lab (IPARR) and our new Neuromotor Assessment Center; and iii) Nationwide Children's Hospital (in Columbus), consistently rated as a “top ten” best children's hospital with a strong commitment to discovery and an active portfolio of NIH pediatric rehabilitation trials from the neonatal period through adolescence. The collaborations will build upon our team's presentations at major scientific meetings with planned follow-up activities (see Didactic Interactions), our close work with recipients of small grants (see Pilot Studies), and our team members' vigorous engagement in Clinical and Translational Science Awards (CTSAs) and national and international special research interest groups and NIH research networks, most centrally StrokeNet. Specific aims for Mentored Collaborative Opportunities are: 1) to identify individuals and research teams well-positioned to make high-impact and novel contributions to pediatric medical rehabilitation research. We seek to develop individually-tailored mentored collaborations to strengthen the breadth and depth of knowledge and research skills among the collaborators; and 2) to provide intensive mentored collaborative experiences that focus on increasing the competencies of investigators and the quality of their competitive applications in pediatric rehabilitation research. These include a mix of educational and hands-on opportunities that will support Phase I through Phase III clinical trials, comparative effectiveness and practice-based research, focused methods research, and Implementation Science trials. We will document all mentored collaborative opportunities we provide and solicit timely feedback from users about the effectiveness and impact of the supports from our National Pediatric Rehabilitation Resource Center (PedRehab Ctr). We reserve modest funding to help with some research expenses (e.g., specialized materials and travel), although home institutions are expected to provide the majority of support for participants.