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中文摘要
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尤尼斯·肯尼迪·施莱弗国家儿童健康和人类发展研究所 (NICHD)寻求支持国际和国内儿科和产妇艾滋病毒的临床活动 以及其他高度优先的传染病。NICHD为其他一些临床试验网络提供临床试验地点,例如 国际母婴青少年艾滋病临床试验小组 IMPAACT网络及其领导小组负责他们所有研究的创建, 方案和临床试验。这些活动通过赠款/合作协议提供资金。 由国家过敏和传染病研究所(NIAID)赞助。这个 IMPAACT网络是一个由机构、调查人员和其他人员组成的合作小组 合作者主要集中在评估艾滋病毒感染的潜在治疗方法及其 婴儿、儿童、青少年和孕妇的相关症状和合并感染对孕产妇健康的影响。 这包括预防母婴传播的艾滋病毒/艾滋病干预措施的临床试验。 变速箱。 1990年,NICHD开始与儿科艾滋病临床试验小组合作, (PACTG)扩大NICHD临床试验中心/站点的临床试验可用性。这 合作使IMPAACT网络能够进行临床试验,以进一步 评估抗逆转录病毒治疗药物和其他针对机会性感染的治疗方法, 以及预防围产期艾滋病毒传播的干预措施。近年来,双方的合作是 扩大以评估潜在的艾滋病毒治愈方法和疫苗。NICHD将 继续向IMPAACT网络提供该协调中心的合同支持 提供对感兴趣的站点和临床人群的访问。 范围 根据IMPAACT相关协议进行临床试验,维护多站点网络 国内外临床中心开展治疗、预防、诊断、 湖北省HIV感染者和疾病及其感染性和非传染性并发症的流行病学 儿科、青少年和产妇患者群体。
英文摘要
The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) seeks to support clinical activities for international and domestic pediatric and maternal HIV and other high priority infectious diseases. NICHD provides clinical trial sites to some other clinical trial networks such as the International Maternal Pediatric Adolescent AIDS Clinical Trials Group (IMPAACT) The IMPAACT network and its leadership group are in charge of the creation of all their studies, protocols, and clinical trials. These activities are funded through Grants/Cooperative agreements sponsored by the National Institute of Allergy and Infectious Diseases (NIAID). The IMPAACT Network is a cooperative group of institutions, investigators, and other collaborators mainly focused on evaluating potential therapies for HIV infection and its related symptoms and co-infections in infants, children, adolescents and pregnant women for maternal health. This includes clinical trials of HIV/AIDS interventions for the prevention of mother to child transmission. In 1990 the NICHD began collaborating with the Pediatric AIDS Clinical Trials Group, (PACTG) to expand clinical trial availability at NICHD clinical trial centers/sites. This collaboration made possible to conduct clinical trials by the IMPAACT Network to further evaluate antiretroviral therapeutic agents, other therapies targeted at opportunistic infections, and interventions to prevent perinatal HIV transmission. In recent years, the collaboration is expanding to evaluate potential HIV cure approaches and vaccines. The NICHD will continue providing this Coordinating Center Contract support to the IMPAACT Network providing access to sites and the clinical populations of interest. Scope To perform clinical trials according to the IMPAACT Related protocols maintaining a multi-site network of domestic and international clinical centers to conduct the research on treatment, prevention, diagnosis, epidemiology of HIV infection and disease and its infectious and non-infectious complications in pediatric, adolescent, and maternal patient populations.
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SUPPORT SERVICES FOR THE PREVENTION AND TREATMENT THROUGH A COMPREHENSIVE CARE CONTINUUM FOR HIV-AFFECTED ADOLESCENTS IN RESOURCE CONSTRAINED SETTINGS IMPLEMENTATION SCIENCE NETWORK
  • 批准号:
    10917617
  • 项目类别:
  • 资助金额:
    $146.15万
  • 财政年份:
    2023
  • 负责人:
    BARBARA DRIVER
  • 依托单位:
SUPPORT SERVICES FOR HIV AIDS CLINICAL TRIAL NETWORKS
  • 批准号:
    10872942
  • 项目类别:
  • 资助金额:
    $272.52万
  • 财政年份:
    2023
  • 负责人:
    BARBARA DRIVER
  • 依托单位:
CORE NICHD NETWORK CLINICAL SITE SUPPORT FOR IMPAACT RELATED STUDIES
  • 批准号:
    10792687
  • 项目类别:
  • 资助金额:
    $242.04万
  • 财政年份:
    2022
  • 负责人:
    BARBARA DRIVER
  • 依托单位:
STUDY CLOSEOUT FOR THE INTERNATIONAL COHORT STUDY OF CHILDREN BORN TO WOMEN INFECTED WITH ZIKA VIRUS DURING PREGNANCY (ZIP 2.0)
  • 批准号:
    10701122
  • 项目类别:
  • 资助金额:
    $50.0万
  • 财政年份:
    2022
  • 负责人:
    BARBARA DRIVER
  • 依托单位: