Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

项目摘要 FDA关于烟草和尼古丁监管的综合计划侧重于两个关键行动：1)减少 可燃香烟中的尼古丁水平，使其最小或不会上瘾；2)允许新形式的香烟 尼古丁的传递，为成年吸烟者提供尼古丁，其产生的健康危害比香烟更低。这个 FDA拟议的尼古丁减少政策对公共健康的影响取决于烟草使用者和 非吸烟者了解尼古丁对特定产品(如电子烟、尼古丁)的危害 替代疗法(NRT)、减少尼古丁含量(RNC)香烟)以及这如何影响决策 非用户试用产品，以及用户停止使用、更换产品或继续使用。人口 数据，包括我们小组最近的工作，突显了公众对尼古丁健康风险的普遍误解 这可能会破坏FDA综合计划对公众健康的好处。因此，FDA的引入 减少一些烟草产品中的尼古丁，而不对其他烟草产品进行监管的政策可能需要更多 关于尼古丁的细致入微的公共教育。我们试点工作的发现支持一种简单的尼古丁矫正剂 消息传递干预-类似于可能在警告标签或公共教育媒体上看到的消息 活动-可以纠正在线上对尼古丁、NRT、电子烟和RNC香烟的误解 方便的美国成年人样本。拟议的研究扩展了我们的试点工作，以检查多个 暴露于尼古丁纠正性信息(NCM)干预(与延迟干预对照相比) 在两个平行和互补的样本中，尼古丁信念和烟草和尼古丁产品的意图/使用。 一项基于人群的研究将评估NCM对尼古丁信念和烟草的潜在公共健康影响。 715名成年吸烟者和非吸烟者的相关行为意向，包括潜在的意外影响。一个 基于实验室的研究将评估NCM和RNC香烟的独立影响以及它们之间的相互作用， 160名成年吸烟者的尼古丁信念和观察到的烟草使用行为 有正常的尼古丁含量或RNC香烟(即，未失明)。这项研究旨在提供对真实情况的洞察 NCM传播努力对普通人群和成人烟草使用行为的世界影响 受可燃香烟尼古丁含量标准降低影响的吸烟者。这项研究将测试一组 关于尼古丁的循证信息，提供关于未来可能使用的内容和主题的信息 对公众进行尼古丁教育，以最大限度地提高FDA综合计划对公众健康的益处。

PROJECT ABSTRACT FDA’s comprehensive plan on tobacco and nicotine regulation focuses on two key actions: 1) reducing nicotine levels in combustible cigarettes to make them minimally or non-addictive and 2) allowing for new forms of nicotine delivery to provide adult smokers with nicotine with lower resulting health harms than cigarettes. The public health impact of FDA’s proposed nicotine reduction policy hinge on the extent to which tobacco users and non-users understand the harms of nicotine in relation to specific products (e.g., e-cigarettes, nicotine replacement therapy (NRT), reduced nicotine content (RNC) cigarettes) and how this influences decisions made by non-users to try a product and by users regarding cessation, product switching, or continued use. Population data, including recent work by our group, highlight widespread public misperceptions of the health risks of nicotine that could undermine the public health benefits of FDA’s comprehensive plan. As a result, the introduction of FDA policies that reduce nicotine in some tobacco products while leaving it unregulated in others may require more nuanced public education about nicotine. Findings from our pilot work support that a brief nicotine corrective messaging intervention—similar to the messages likely to be seen on warning labels or in public education media campaigns—can correct misperceptions of nicotine, NRT, e-cigarettes, and RNC cigarettes in an online convenience sample of U.S. adults. The proposed study extends our pilot work to examine the effect of multiple exposures to nicotine corrective messaging (NCM) intervention (compared to a delayed intervention control) on nicotine beliefs and intention/use of tobacco and nicotine products in two parallel and complementary samples. A population-based study will estimate the potential public health impact of NCM on nicotine beliefs and tobacco- related behavioral intentions in 715 adult tobacco users and non-users, including potential unintended effects. A lab-based study will estimate the independent effects of NCM and RNC cigarettes, as well as their interaction, on nicotine beliefs and observed tobacco use behavior in 160 adult smokers who are explicitly told whether they have a normal nicotine content or RNC cigarette (i.e., unblinded). This study aims to provide insight into the real world impact of NCM communication efforts on tobacco use behavior in the general population and in adult smokers affected by a reduced nicotine content standard in combustible cigarettes. This study will test a set of evidence-based messages on nicotine, providing information on content and themes that could be used in future public education on nicotine to maximize the public health benefit of FDA’s comprehensive plan.