Tuskegee University Center for Biomedical Research/ Research Centers at Minority Institutions

项目总结/摘要 塔斯基吉大学生物医学研究中心的总体目标是： 少数民族机构（TU CBR/RCMI）计划是建立和发展大学的研究 基础设施和研究人员进行与健康差距有关的研究。该举措以 1）提供必要的基础设施、资源、服务和技术支持， 该大学的研究人员保持在多学科生物医学研究的前沿的能力 重点关注健康差距，2）支持初级和中级研究和职业发展 investigators.这些目标主要通过以下目标实现：1）提供试点 资助支持发展和扩大TU的生物医学研究能力; 2）提供 核心研究设施配备了基础设施，仪器和人员，以支持 TU研究社区的需求; 3）通过RCMI赞助的活动参与社区， 包括研究人员;以及4）提供导师和职业指导，以促进 初级调查员转变为独立科学家。CBR/RCMI项目的总体目标（2017-2022年） 是继续发展其基础设施，增加少数民族的数量和技能熟练程度， 从事先进生物医学研究的科学家专注于健康差距，包括艾滋病毒， 肥胖和前列腺癌，所有这些都不成比例地影响非洲裔美国人， 代表性不足的少数民族。换句话说，目标是继续支持一个有竞争力的、多学科的 促进生物医学研究的协作环境。塔斯基吉大学有着独特的优势 因为它位于东南部的中心，这个地区有一个巨大的，历史上服务不足的非洲国家， 美国人口，它有大量的少数民族教师以及本科生和 毕业实习生社区康复/区域协调机制的目标将通过建立三个协同机制来实现。 研究中心，提供服务，以便能够对少数群体的卫生不公平现象进行调查研究， 特别是居住在亚拉巴马“黑带”县的非洲裔美国人。这些核心创造了一个刺激的 环境，促进高效和及时的行政支助文化， 资金提交和/或获取生物医学和社区参与的校外资金 research.行政核心将通过授标前和授标后服务提供多功能支助; 目标、方向和指导的实施;以及监督，以确保具体目标和 目标已经实现。此外，研究者发展核心将支持 额外的研究领域，同时通过高级导师加强初级教师的成长， 生物伦理学培训。此外，通过我们的社区参与核心，我们将建立关系，建立信任， 让当地社区和社区组织参与进来， 对影响他们的健康问题。我们还将实施一项评估计划， 五年的进展，生产力，并通过使用形成性和总结性的CBR问责制 结果。其结果是增加，通过批准和可执行的协议，重点是初级教师 发展和生产力，R型赠款的数量和同行出版物的数量， 审查期刊。先进的研究设备，加上新的知识 由TU博士生，科学家和合作者产生的将有助于减少健康差距 在亚拉巴马的黑带县。

PROJECT SUMMARY/ABSTRACT The overall objective of the Tuskegee University Center for Biomedical Research/Research Centers in Minority Institutions (TU CBR/RCMI) Program is to build upon and develop the University’s research infrastructure and researchers to conduct research related to health disparities. This initiative is centered around: 1) providing the necessary infrastructure, resources, services, and technical support to enhance the ability of the University’s researchers to stay on the cutting-edge of multidisciplinary biomedical research focused on health disparities and 2) supporting the research and career development of junior- and mid-level investigators. These objectives are to be achieved primarily through the following aims: 1) Provide pilot-level funding to support the development and expansion of the biomedical research capacity of TU; 2) Provide core research facilities equipped with the infrastructure, instrumentation, and personnel to support the needs of the TU research community; 3) Engage the community through RCMI-sponsored activities that include the research faculty; and 4) Provide mentorship and career guidance to enhance the transition of junior-level investigators into independent scientists. The overall goal of the CBR/RCMI project (2017-2022) is to continue the development of its infrastructure and increase the numbers and skill proficiency of minority scientists engaged in advanced biomedical research focused on health disparities, including those for HIV, obesity, and prostate cancer, all of which disproportionately affect African Americans and underrepresented minorities. In other words, the goal is to continue support for a competitive, multidisciplinary collaborative environment that advances biomedical research. Tuskegee University has distinctive strengths because it is located in the heart of the Southeast, a region with a large, historically underserved, African American population, and it has a large number of minority faculty members as well as undergraduate and graduate trainees. The goal of the CBR/RCMI will be accomplished through establishment of three synergistic research cores, with services to enable investigative research on health inequities among minority groups, especially African-Americans residing in the ‘Black Belt’ counties of Alabama. These cores create a stimulating environment that promotes a culture of efficient and timely administrative support that will increase the number of funding submissions and/or acquisitions of extramural funding in biomedical and community engagement research. The Administrative Core will provide multi-functional support through pre- and post-award services; implementation of objectives, directions, and guidance; and oversight to ensure that specific aims and objectives are accomplished. Additionally, the Investigator Development Core will support the development of additional areas of research while enhancing the growth of junior faculty through senior mentorship and bioethics training. Further, through our community engagement core, we will establish relationships, build trust, and engage local communities and community-based organizations to learn from and to educate community members on health issues that affect them. We will also implement an evaluation plan to assess, over a period of five years, the progress, productivity, and accountability of the CBR by using both formative and summative outcomes. The outcome is to increase, by an approved and enforceable protocol that focuses on junior faculty development and productivity, the number of R-type grants awarded and the number of publications in peer- reviewed journals. The availability of advanced research equipment, coupled with the new knowledge generated by TU PhD students, scientists, and collaborators will contribute to the reduction of health disparities in the Black Belt counties of Alabama.