Pilot Projects Program

试点项目计划项目摘要 试点项目计划(PPP)管理资助机制，以开发和支持最有希望的 以及由研究人员发起的新的临床和转化研究(CTR)项目。我们的首要目标是 提供调查人员初步生成所需的财务支持、指导和其他资源 数据，并成功争取到外部赠款资金。该程序被设计为进一步的4键 目标：1)促进成功的CTR调查人员的发展；2)支持和发展 跨学科CTR团队，3)开发创新工具和技术，以支持远程实施 CTR或改善健康结果，以及4)支持评估与健康相关的各种原因的CTR 该地区的贫富差距。购买力平价通过两个具体目标支持这些总体目标：具体目标1) 管理CTR试点项目计划，以促进创新和协作的CTR计划和 具体目标2)与核心和伙伴机构合作，提供发展CTR资源，以 扩大CTR调查人员和团队的队伍。为了成功实现这些具体目标，公私合作伙伴关系支持 跨学科、基于团队的研究，跨越整个CTR的所有GP IDEA-CTR合作机构 频谱。在过去四年的经验教训和成功经验的基础上，提供的购买力平价组合 资助机会将从战略上扩大到包括：1)团队发展试点，以提供初始 为培养新团队提供资金，2)团队研究试点，为现有的CTR团队提供资金，以及 3)技术转让试点，支持将知识产权转化为临床和社区应用。 将利用伙伴机构的资源来增加可用奖项的数量以及 基金专科奖侧重于特定疾病(例如，癌症或心血管疾病)。试点项目 计划将与所有核心合作，以推进CTR，包括生物统计学、流行病学和 研究设计(BERD)核心和社区参与和外联(CEO)核心试点拨款 加强数据科学和试验设计研究以及以社区为基础的能力的机会 CTR项目，并与职业发展(PDC)核心一起扩大对飞行员的培训和指导 授予接受者。结合起来，这些跨学科、跨竖井的努力将进一步加强 为了我们所有合作机构的CTR并取得成功，加强对专注于CTR的教师的当地支持，以及 鼓励可持续的内部和机构间CTR合作，以改善#年的健康结果 内布拉斯加州和大平原。

Pilot Projects Program Project Summary The Pilot Projects Program (PPP) administers funding mechanisms to develop and support the most promising and novel investigator-initiated clinical and translational research (CTR) projects. Our overarching goal is to provide the financial support, mentoring, and other resources that investigators need to generate preliminary data and successfully compete for extramural grant funding. The program is designed to further 4 key objectives: 1) to foster the development of successful CTR investigators, 2) to support and develop interdisciplinary CTR teams, 3) to develop innovative tools and technologies that will support remote conduct of CTR or improve health outcomes, and 4) support CTR that evaluates the diverse causes of health-related disparities in the region. The PPP supports these overall objectives through two specific aims: Specific Aim 1) administer a CTR Pilot Projects Program that facilitates innovative and collaborative CTR programs and Specific Aim 2) collaborate with the Cores and partner institutions to provide developmental CTR resources to expand the pool of CTR investigators and teams. To successfully meet these specific aims, the PPP supports interdisciplinary, team-based research that spans all GP IDeA- CTR partner institutions across the CTR spectrum. Building on lessons learned and successes over the past four years, the portfolio of offered PPP funding opportunities will be strategically expanded to include: 1) Team Development Pilots to provide initial funding to foster new team formation, 2) Team Research Pilots to provide funding to existing CTR teams, and 3) Tech Transfer Pilots to support translation of intellectual property into clinical and community applications. Resources from partner institutions will be leveraged to increase the number of available awards as well as fund specialty awards focused on specific diseases (e.g., cancer or cardiovascular disease). The Pilot Projects Program will collaborate with all Cores to advance CTR, including the Biostatistics, Epidemiology and Research Design (BERD) Core and Community Engagement and Outreach (CEO) Core on their pilot grant opportunities to strengthen the capacity for data science and trial design research as well as community-based CTR projects, and with the Professional Development (PDC) Core to expand training and mentoring for pilot grant recipients. In combination, these interdisciplinary, silo-spanning efforts will further strengthen the capacity for and success of CTR across all our partner institutions, reinforce local support for CTR-focused faculty, and encourage sustainable intramural and interinstitutional collaboration on CTR for improved health outcomes for Nebraska and across the Great Plains.