Exercising Together: A Randomized Controlled Trial of Partnered Exercise Training on the Health of Couples Coping with Cancer-Promote Diversity

补充摘要 常见癌症-前列腺癌（PC）、结直肠癌（CRC）或乳腺癌（BC）的非裔美国人（AA）幸存者- 与非西班牙裔白色幸存者相比， 健康受到不利影响。研究改善AA结果的策略的影响及其 亲密伴侣是稀缺的。有针对性的招聘，其中包括文化相关的战略可能会有所帮助 与AA参与者的兴趣/愿意被筛选和参与夫妇为基础的研究。的 家长对这种补充剂的资助是一项疗效试验（一起锻炼试验; R 01 CA 218093），以确定 团队合作的好处，通过一个合作的锻炼计划，对身体，情感和关系 癌症幸存者及其亲密伴侣的健康状况。在母研究中入组AA夫妇， 未达到预期比率，为补充项目提供了雇用社区参与者的机会 和文化相关的战略，以提高登记AA夫妇应对癌症的父母研究 也是为将来的试验收集初步数据的动力，特别是在AA夫妇应对癌症的试验中。 该研究项目将在美国的两个不同地区使用社区参与工作室方法。 （太平洋西北部和东南部），以确定促进者和AA夫妇参与夫妇的障碍- 基于运动研究，特别是在一起锻炼协议。社区参与工作室 将在波特兰，OR（告知母研究的调整）和诺克斯维尔，TN（提供 未来的研究方向）。调查人员将使用来自社区参与工作室的信息， 制定、实施和评估与文化相关的招聘战略， 共同计划，将促进AA夫妇应对癌症的参与。该补充还 支持培训一名年轻的、代表性不足的研究人员，以增加癌症的多样性， 健康相关的研究人员。培训机会将加强受训者的技能， 社区参与的方法，以适应AA夫妇与癌症的计划。该补充将提供 受训者有了一个新的机会与癌症幸存者及其亲密伴侣一起工作， 可以从父母研究的二元方法中在身体和情感上受益。这使 受训者朝着她的目标，减少健康差距，并推进她的培训，介绍一个重要的 临床人群的发病率和死亡率在美国的经验将达到高潮， 提交一份独立的赠款提案，结合导师和技能， 补充提供，将有助于引导她朝着她的目标，实现独立资助的研究 程序.总之，这种独特的和文化相关的夫妇为基础的方法可以增加的潜力， 母公司研究的影响，以及本补充的总体工作最终可能有助于减少 癌症差异

Supplement Abstract African American (AA) survivors of common cancers - prostate (PC), colorectal (CRC), or breast cancer (BC) - have poorer outcomes than non-Hispanic White survivors and if married, spouse/partner and relationship health is adversely impacted. Research studying the impact of strategies to improve outcomes in AAs and their intimate partners is scarce. Targeted recruitment which incorporates culturally relevant strategies may help with AA participants’ interest in/willingness to be screened for and participate in couples-based research. The parent grant to this supplement is an efficacy trial (the Exercising Together trial; R01CA218093) to determine the benefits of teamwork, through a partnered exercise program, on physical, emotional, and relationship health among cancer survivors and their intimate partners. Enrollment of AA couples in the parent study has fallen short of anticipated rates, providing an opportunity for supplement project to employ community-engaged and culturally relevant strategies to enhance enrollment of AA couples coping with cancer in the parent study and also an impetus to collect preliminary data for a future trial specifically in AA couples coping with cancer. The research project will use a Community Engagement Studio approach in two different regions of the U.S. (Pacific Northwest and Southeast) to identify facilitators and barriers to AA couples’ participation in couples- based exercise research and specifically in the Exercising Together protocol. Community Engagement Studios will be conducted in Portland, OR (to inform adaptations to the parent study) and Knoxville, TN (to provide context for future research). Investigators will use information from the Community Engagement Studio to develop, implement, and evaluate culturally relevant recruitment strategies and delivery of the Exercising Together program that will promote engagement of AA couples coping with cancer. This supplement also supports training for a young, underrepresented investigator in an effort to increase diversity in the cancer- and health-related research workforce. The training opportunity will strengthen the trainee’s skillset in using community-engaged approaches to adapt a program for AA couples with cancer. This supplement will provide the trainee with a new opportunity to work with cancer survivors and their intimate partners, a demographic that can benefit both physically and emotionally from the dyadic approach of the parent study. This moves the trainee toward her goal of reducing health disparities and advances her training to introduce an important clinical population in terms of incidence and mortality in the U.S. The experience will culminate in the submission of an independent grant proposal that in combination with the mentorship and skills this supplement provides, will help steer her toward her goal of achieving an independently funded research program. In summary, this unique and culturally relevant couples-based approach could increase the potential impact of the parent study, and the work of this supplement overall could ultimately contribute to reduced cancer disparities.