Admin Core

项目摘要/摘要(行政核心彭宁顿/路易斯安那州NORC) 彭宁顿/路易斯安那州营养肥胖研究中心(NORC)的主题是“营养、肥胖和 生命周期中的代谢健康“。我们的NORC最初成立于2005年，旨在促进和促进 协同多学科互动，培育新的研究思路，提升《基础》翻译 营养学研究成果进入临床领域和实际应用。像大多数NIDDK NORC一样， 我们的研究基础与营养对健康和疾病的代谢后果有关。我们的NORC 为营养和营养疾病的病理生理学、治疗和预防研究提供核心科学资源 与肥胖相关的疾病，并跨越从细胞到社会的研究范围。彭宁顿/路易斯安那州 NORC为我区与肥胖相关的生物医学研究提供基础性支持。北大西洋公约组织 管理核心提供了凝聚力，在我们的主题内连贯地统一了我们的教职员工，提供了他们 拥有生物医学核心设施进行研究，使他们在未来的科学研究中具有竞争力 致力于并吸引新的和初级的研究人员进入营养和肥胖研究领域。这个 管理核心有以下目标：1)提供促进成功的管理基础设施 以及三个科学核心资源(人类表型， 分子机制，动物模型和表型)，试点和可行性(P&F)资助计划，以及 充实计划，2)提高营养、肥胖和代谢研究的质量和数量 通过我们的机构和合作机构继续吸引有经验的和 初级教员与最新的研究技术一起，对营养与肥胖的研究进行征集、综述 选择试点和可行性项目，4)协助和监督项目设计和统计分析 NORC所有成员在基础、临床和人口科学方面进行的实验研究，以及5) 管理生物标本和人类研究数据的收集和存储。我们的NORC是一个复杂的 该组织由63名正式成员组成，他们的赠款包括我们2020年的研究基础资金 &gt；4400万美元的直接成本；所有这些成本都分享了我们的NIDDK P30 NORC赠款提供的核心资源；加上 合作会员70人，辅导会员13人。我们的执行领导团队实现了我们的目标 每月召开会议，以确定NORC的总体方向，并监督NORC资源的最佳利用。 我们的内部咨询委员会(IAB)每6个月召开一次会议，提供NORC成员的反馈意见，建议 新的发展和服务，并就核心服务的使用提供咨询。每隔12-24个月，欧盟委员会和IAB 与我们的外部咨询委员会(EAB)面对面会面。

PROJECT SUMMARY/ABSTRACT (ADMINISTRATIVE CORE PENNINGTON/LOUISIANA NORC) The theme of the Pennington/Louisiana Nutrition Obesity Research Center (NORC) is "Nutrition, Obesity and Metabolic Health through the Lifespan". Our NORC was initially established in 2005 to facilitate and promote collaborative and multi-disciplinary interactions, foster new research ideas, and enhance the translation of basic nutritional research findings into the clinical arena and practical applications. Like most of the NIDDK NORCs, our research base is related to the metabolic consequences of nutrition on health and diseases. Our NORC provides core scientific resources for research in the pathophysiology, treatment and prevention of nutrition and obesity-related diseases and spans the research spectrum from cells to society. The Pennington/Louisiana NORC provides foundational support for obesity-related biomedical research in our region. The NORC Administrative Core provides the adhesion that coherently unifies our faculty within our theme, provides them with biomedical core facilities to perform their studies, makes them competitive for their future scientific endeavors, and attracts new and junior investigators into the field of nutrition and obesity research. The Administrative Core has the following aims: 1) provide the administrative infrastructure that facilitates successful and optimized performance of and interactions between the three scientific core resources (Human Phenotyping, Molecular Mechanisms, and Animal Models & Phenotyping), the Pilot and Feasibility (P&F) Grant Program, and the Enrichment Program, 2) increase the quality and quantity of research on “Nutrition, Obesity and Metabolic Health through the Lifespan” at our and collaborating institutions by continuing to attract both experienced and junior faculty, together with the latest research technologies, to the study of nutrition and obesity, 3) solicit, review and select pilot and feasibility projects, 4) assist with and supervise the design and statistical analysis of experimental studies performed by all NORC members in basic, clinical and population sciences, and 5) administer the collection and storage of bio-specimens and data from human research. Our NORC is a complex organization consisting of 63 Regular Members whose grants comprise our 2020 Research-Base funding of >$44 million direct costs; all of whom share in the core resources provided by our NIDDK P30 NORC grant; plus 70 Collaborating Members and 13 Mentored Members. Our executive leadership team accomplishes our aims by meeting monthly to set the overall direction of the NORC and oversee optimal utilization of NORC resources. Our Internal Advisory Board (IAB) meets every 6 months to provide feedback from the NORC members, suggest new developments and services and advise on the use of core services. Every 12-24 months, the EC and IAB meet face-to-face with our External Advisory Board (EAB).