模拟建模支持北美阿片类药物危机的公共卫生应对-猫眼课题宝

模拟建模支持北美阿片类药物危机的公共卫生应对

批准号：

10409779

负责人：

Natasha Martin

金额：

$2.47万

依托单位：

WEILL MEDICAL COLL OF CORNELL UNIV

依托单位国家：

美国

项目类别：

财政年份：

2021

资助国家：

美国

项目状态：

已结题

起止时间：

2021-06-01 至 2024-05-31

来源：

https://reporter.nih.gov/project-details/10409779

关键词：

Accounting Address Affect American Automobile Driving Bacterial Infections COVID-19 pandemic Calibration Canada Case Study Centers for Disease Control and Prevention (U.S.)Cessation of life Collaborations Communities Complex Conflict (Psychology)Country Data Decision Making Drug usage Educational workshop Ensure Environment Fentanyl Funding Future Goals HIV HIV Infections HIV/HCV Health Health Policy Hepatitis C Hepatitis C virus Heroin High Prevalence Illicit Drugs Individual Institutes Intervention Investments Joints Knowledge Manuscripts Measures Medical Societies Methodology Methods Mexico Modeling National Institute of Drug Abuse North America Opioid Outcome Overdose Pattern Pharmaceutical Preparations Policies Policy Analysis Policy Maker Policy Making Population Production Public Health Publications Research Research Personnel Resources Role Route Science Secure Shapes Speed Stigmatization Structure Time Translations United States National Institutes of Health Vietnam Violence War Writing data sharing dissemination strategy evidence base improved in silico injection drug use innovation interest knowledge translation meetings methamphetamine use model design models and simulation mortality multiple data sources opioid epidemic opioid injection opioid use opioid use disorder overdose death response simulation soft tissue syndemic trafficking webinar working group

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中文摘要

翻译

项目总结 2018年，美国有近4.7万人死于阿片类药物--几乎相当于整个越南战争。注射阿片类药物和甲基苯丙胺的使用正在推高艾滋病毒和丙型肝炎病毒的感染率。阿片类药物危机同样影响到加拿大和墨西哥，导致呼吁对北美采取行动解决阿片类药物危机。仿真模型为决策者提供了一个结构化的环境比较拟议的政策替代方案在较长时间范围内对人口的预测影响- 水平结果，如过量用药、艾滋病毒和丙型肝炎病毒。新冠肺炎大流行为这一效用提供了证据使用模拟模型进行公共卫生决策。几个公共机构目前正在资助北美的阿片类药物模拟建模工作，包括NIDA、CDC、FDA、加拿大研究所健康研究(CIHR)和加拿大省级机构。我们的首要目标是提高知识翻译的速度、有效性和有效性，以及

英文摘要

PROJECT SUMMARY Opioids were involved in almost 47,000 deaths in the U.S. in 2018—nearly the number who were killed in the entire Vietnam War. Injection opioid and methamphetamine use are driving up rates of HIV and HCV infection. The opioid crisis has similarly affected Canada and Mexico, leading to a call for a North American approach to addressing the opioid crisis. Simulation models provide a structured environment for decision makers to compare the predicted effects of proposed policy alternatives over an extended time horizon on population- level outcomes such as overdose, HIV, and HCV. The COVID-19 pandemic has provided evidence of the utility of using simulation models for public health decision making. Several public agencies are currently funding opioid simulation modeling efforts in North America, including NIDA, CDC, FDA, the Canadian Institutes of Health Research (CIHR), and Canadian provincial agencies. Our overarching goal is to improve the speed, validity, effective knowledge translation, and

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