Bioengineering Cardiovascular Training Grant (BCTG)

摘要 生物工程心血管培训补助金（BCTG）计划为六个NIH提供生物工程培训。 支持和一个生物工程系支持博士生致力于心血管事业 research.心血管（CV）疾病是美国死亡的主要原因，该领域的进展 将需要培养具有各种生物工程背景的杰出科学家，以开发新的， 研究、诊断和治疗心血管疾病的创新方法。华盛顿大学和 50多年来，生物工程一直是CV研究和技术开发的领导者。BCTG教师 在工程学院和医学院的多个部门有很强的合作计划 在这个领域。我们的计划通过培训基础科学和转化研究的专业人员使公众受益 它整合了工程学、数学、化学、生理学、物理学和计算技能， 基础性发现和开发新技术。学生获得跨学科的技能和价值 协作该计划强调新技术的发展，在诊断和治疗研究 治疗心血管疾病，改善早期发现和疾病管理，提高心脏病患者的生活质量 失败的病人我们认为，转化研究的成功需要训练有素的科学家， 被放置在学术界和工业界，具有成功地将研究从大学过渡到 商业化和临床。对于此更新提案，我们添加了几个新组件，以提供 在研究和专业技能的培训，跨越生物医学管道从发现和机械 研究到转化研究再到商业化或临床开发。2年计划包括1） 在选定的导师的实验室研究，2）一个独特的课程与临床培训的机会， 翻译和商业化，和3）临床preceptorships是独特的，我们的计划。学员参加 每周一次的研讨会系列，重点是简历研究，与相关的期刊俱乐部和特别会议， 演讲者仅限于学员。学员还参加生物医学中心的讲座和讨论小组。 研究诚信暑期项目，由医学院主办。其他新组件包括 对代表性不足的群体进行外联和研究指导，以增加STEM劳动力的多样性 领域，并提供专业技能发展和培训资源和研讨会的课程， 研究的可重复性、严谨性和透明度。学员的选择是基于强大的定量和 工程背景，教师导师的培训环境，研究对我们的适当性 计划重点和创新，合作和转化研究的潜力。出席的受训人员 在年度研讨会和国家会议上，并撰写年度进度报告，其中包括反馈问题 不断改进我们的计划。学员须在两年期结束时申请研究金。 培训期间，开始建立一个成功的竞争，在获得研究支持的记录。

ABSTRACT The Bioengineering Cardiovascular Training Grant (BCTG) program provides Bioengineering training for six NIH supported and one Bioengineering department supported PhD students committed to careers in cardiovascular research. Cardiovascular (CV) diseases are the leading cause of mortality in the US and progress in this area will require training outstanding scientists with a variety of backgrounds in bioengineering to develop new and innovative approaches for study, diagnosis and treatment of CV disease. The UW and Department of Bioengineering have been leaders in CV research and technology development for over 50 years. BCTG faculty in multiple departments in the College of Engineering and School of Medicine have strong collaborative programs in this area. Our program benefits the public by training professionals in basic science and translational research that integrates engineering, mathematics, chemistry, physiology, physics and computational skills to promote fundamental discoveries and develop new technologies. Students gain interdisciplinary skills and the value of collaboration. The program emphasizes new technology development in diagnostics and therapeutics to study and treat CV pathologies, improving early detection and disease management, to improve quality of life for heart failure patients. We believe that the success of translational research requires highly trained scientists to be placed in both academia and industry, with skills to successfully transition research from universities to commercialization and the clinic. For this renewal proposal we have added several novel components to provide training in research and professional skills that spans the biomedical pipeline from discovery & mechanistic studies to translational research to commercialization or clinical development. The 2-year program involves 1) research in the laboratory of a chosen mentor, 2) a unique curriculum with opportunities for training in clinical translation and commercialization, and 3) clinical preceptorships that are unique to our program. Trainees attend a weekly seminar series focused on CV research, with an associated journal club and special sessions with speakers that are limited to trainees. Trainees also attend lectures and discussion groups in the Biomedical Research Integrity summer program, sponsored by the School of Medicine. Additional new components include outreach and research mentoring to under-represented groups to increase the diversity of the workforce in STEM fields, and a course that provides resources and seminars for professional skills development and training in research reproducibility, rigor and transparency. Trainees are selected based on strong quantitative and engineering backgrounds, training environment of faculty mentors, appropriateness of the research to our programmatic focus and the potential for innovative, collaborative and translational research. Trainees present at yearly symposiums and national meetings, and write a yearly progress report that includes feedback questions to continually improve our program. Trainees are required to apply for fellowships at the end of the two-year training period to begin establishing a record of successful competition in gaining research support.