Intelligent Wearable Analyzer for Vapor Exposure (iWAVE) in Transportation Sector

交通行业智能可穿戴式蒸汽暴露分析仪(IWave) 接触有害空气污染物(HAPS)与多种健康影响有关，如癌症、 哮喘、自闭症、生育力下降和智力低下。制定有效的减排战略 职业性接触HAPS需要准确的、时间分辨的暴露测量。现行做法 通常需要使用罐或吸收管在野外采集样本，然后将其运送到实验室，以及 然后应用带有检测器的气相色谱来鉴定和定量存在于 环境。一种小型、不显眼、可穿戴的直读设备，曝光时间分辨率为5分钟 评估将加强对工人暴露的监测，并提高我们应对暴露的能力 流行病学研究。拟议的项目将采用微电子机械系统(MEMS)技术， 先进的微电子元件和系统，以及最先进的微气相色谱(µGC) 和电信技术开发智能可穿戴式蒸汽暴露分析仪(IWave)，用于 用于运输、仓储和公用事业(TWU)部门以及其他工人 暴露在类似的化学危险中(跨部门暴露评估)。IWave允许更好地评估 在实时基础上，工作场所条件和活动对HAP产生和随后的影响 曝光。此功能有三个主要结果：(1)允许识别符合以下条件的特定活动 与暴露增加有关，以便最有效地应用缓解努力；(2) 在健康影响研究中大大改善对个人职业暴露的监测；及(3)提供 用于实时检测系统的平台，可以提醒工人注意危险条件。三个具体目标 提议的项目包括：1)包括空气在内的iWave MEMS模块的实施和表征 采样、预富集和进样(ASPI)和多维分离和检测(GC矩阵或 GCM)模块，2)iWave在模拟职业环境下的实施和评估，以及3) IWave验证和利用iWave进行运输部门的风险分析 弗吉尼亚理工大学运输学院(R2P)。30名经验丰富的重型汽车工人正在进行柴油改装 燃料和维护任务将佩戴传统的工业卫生采样列车和iWave 在鼻/口半径0.4米范围内采集呼吸区样本。IWave在以下方面的优势 即使在低浓度(Ppbv)环境中，识别HAP的总分析时间(&lt；5分钟)也将为 演示了。在侧重于暴露监测的同时，该项目的科学和技术影响 如果这项研究成功完成，可能会扩展到其他应用领域。

Intelligent Wearable Analyzer for Vapor Exposure (iWAVE) in Transportation Sector Exposure to hazardous air pollutants (HAPs) has been linked to a variety of health effects, such as cancer, asthma, autism, reduced fertility, and lower intelligence. Development of effective strategies for reducing occupational exposure to HAPs requires accurate, time-resolved measurement of exposure. Current practice typically requires collection of a sample in the field using a canister or sorbent tube, transport to the lab, and then application of gas chromatography with a detector to identify and quantify the species present in the environment. A small, unobtrusive, wearable, direct-read device with 5-min time resolution for exposure assessment would enhance worker exposure monitoring and advance our capabilities for exposure-response epidemiologic study. The proposed project will employ microelectromechanical systems (MEMS) technology, advanced microelectronics components and systems, and state-of-the-art micro gas chromatography (µGC) and telecommunication techniques to develop an intelligent wearable analyzer for vapor exposure (iWAVE) for use in the Transportation, Warehousing, and Utilities (TWU) sector and in others where workers are exposed to similar chemical hazards (Exposure Assessment cross-sector). iWAVE allows to better assess on a real-time basis the effects of workplace conditions and activities on HAP generation and subsequent exposure. This capability has three major outcomes: (1) to allow identification of specific activities that are associated with elevated exposures so that mitigation efforts might be applied most effectively; (2) to enable greatly improved monitoring of personal occupational exposure in health effects studies; and (3) to provide a platform for a real-time detection system that can alert workers to hazardous conditions. Three specific aims for the proposed project are: 1) implementation and characterization of iWAVE MEMS modules including air sampling, preconcentration, and injection (ASPI) and multi-dimensional separation and detection (GC Matrix or GCM) modules, 2) iWAVE implementation and evaluation under simulated occupational environments, and 3) iWAVE validation and utilization for exposure analysis in the transportation sector through the assistance of Virginia Tech Transportation Institute (R2P). Thirty experienced heavy-vehicle workers performing diesel re- fueling and maintenance tasks will wear both conventional industrial hygiene sampling trains and iWAVE for breathing zone sample collection within a 0.4m radius of the nose/mouth. iWAVE superiority in terms of the total analysis time (<5min) for HAP identification even in low-concentration (ppbv) environments will be demonstrated. While focused on exposure monitoring, the scientific and technological impacts of this project may extend to other applications if this research is accomplished successfully.