Building Interdisciplinary Research Careers in Women's Health

项目摘要 这是杜兰BIRCWH计划的竞争更新申请，该计划已成功培训了一名 一群种族/族裔和专业多样的妇女健康和 在过去的4年里，杜兰大学提高了对妇女健康研究的认识。我们现在建议， 我们先前的成功，扩大和加强BIRCWH计划基础。长期目标是增加 受过高度培训的文化能力强、独立、跨学科的调查人员的数量和多样性， 妇女健康，重点是心血管疾病领域的性别/性别差异研究 缓解（CVD）、感染性疾病（ID）和神经科学（NS）。该计划将集中在CVD，ID和NS是- 这些疾病对妇女的影响的原因，现有的关于性/性别差异的知识差距， 以及杜兰大学在这些领域的实力。我们成功的关键因素 职业发展计划包括1）针对特定学者需求的教学课程; 2）个性化的课程， reer发展培训; 3）BIRCWH系列研讨会; 4）工作进展会议; 5）所需的补助金和科学- 有效的写作和项目管理研讨会; 6）指导跨学科研究; 7）负责任的沟通， 在研究训练中发挥作用。创新的方法，包括量身定制的计划，以学者的需要，使用自我， 效能评估和职业发展计划，并对每个学者使用网络指导模式， 包括基础科学和临床研究方面的专业知识。学者们立即接触到研究 并引导建立一个学术跟踪记录早期，并获得交流和组织技能， 积极参与健康科学研究日-妇女健康/性别差异部分。新的COM- 增强的BIRCWH计划的重点包括扩大最近建立的杜兰空军基地的能力 卓越中心在性为基础的生物学和医学（TCESBM）;增加教师参与前， ID和NS的扩展领域;在团队科学和公平，多样性和包容性方面建立学者能力 (EDI)促进对性/性别与社会决定因素之间相互作用的理解 健康（SDOH）。学者们将学习前沿的研究方法和技能，从板凳（细胞，莫- 从学术、遗传学）到临床（临床研究、临床试验）再到人口（流行病学、预防、健康 服务研究），并进行自己的研究项目，在既定的实验室/小组在一个指导， 跨学科环境，解决2019-2023年跨NIH妇女健康战略计划， 搜索学者的跨学科研究将集中在CVD，ID和NS和AD的性别/性别差异， 服装的首要主题（寿命，性/性别决定因素，健康差距，跨学科研究）。 我们建议培训6名教师学者2-3年（3年的医生，科学家的典型）。进行中，com- 深入的评估将指导改进该计划在桥接研究方面的成功 初级学者的培训和研究独立性侧重于CVD，ID和NS的性别/性别差异。

Project Summary This is a competing renewal application for the Tulane BIRCWH Program, which has successfully trained a racially/ethnically and professionally diverse group of interdisciplinary researchers in women’s health and in- creased awareness of women’s health research at Tulane over the last 4 years. We propose now to build on our prior success and expand and reinforce the BIRCWH program base. The long-term goal is to increase the number and diversity of highly trained culturally competent, independent, interdisciplinary investigators in Women’s Health with an emphasis on Sex/Gender Differences research in the fields of cardiovascular dis- ease (CVD), infectious disease (ID) and neuroscience (NS). The program will focus on CVD, ID and NS be- cause of the impacts of these diseases on women, the existing knowledge gaps on the sex/gender differences across the research spectrum, and the strength of these areas at Tulane. Key components of our successful career development plan include 1) didactic courses tailored to specific Scholar needs; 2) individualized ca- reer development training; 3) BIRCWH seminar series; 4) Work-in-Progress sessions; 5) required grant & sci- entific writing and project management workshops; 6) mentored interdisciplinary research; 7) responsible con- duct in research training. The innovative approach includes tailoring the program to Scholars needs using self- efficacy assessment and career development plans, and using a network mentoring model for each Scholar, including expertise in both basic science and clinical research. Scholars are immediately exposed to research and are guided to establish a scholarly track record early, and gain presentation and organization skills by ac- tive participation in the Health Sciences Research days-Women’s Health/Sex Differences Section. New com- ponents of the enhanced BIRCWH program include expanding capacity with the recently established Tulane Center of Excellence in Sex-based Biology and Medicine (TCESBM); increasing faculty participation in ex- panded fields of ID and NS; building Scholar competence in team science and equity,diversity, and inclusion (EDI) in research; and advancing understanding of the interplay between sex/gender with social determinants of health (SDOH). The Scholars will learn cutting-edge research methods and skills from Bench (cellular, mo- lecular, genetics), to Bedside (clinical research, clinical trials) to Population (epidemiology, prevention, health services research) and conduct their own research projects in established laboratories/groups in a mentored, interdisciplinary environment that address the 2019-2023 Trans-NIH Strategic Plan for Women’s Health Re- search. Scholar’s interdisciplinary research will focus on sex/gender differences in CVD, ID, and NS and ad- dress overarching themes (lifespan, sex/gender determinants, health disparities, interdisciplinary research). We propose to train 6 faculty Scholars for 2-3 years (3 years typical for physician-scientists). Ongoing, com- prehensive evaluation will guide improvements to the program's demonstrated success in bridging research training & research independence for junior scholars focused on sex/gender differences in CVD, ID, and NS.