Integrated Training For Physician-Scientists

项目摘要/摘要 威斯康星大学麦迪逊分校(UW-Madison)医学科学家培训计划(MSTP)旨在 培养和培养临床医学和生物医学研究领域的未来领导者和内科科学家。我们的 该计划在多个领域培训不同的学生，课程和培训计划持续进行 通过衡量标准、批判性自我评估和学生意见进行改进。我们计划的指导原则包括： (1)具有相当于单学位候选人的严格程度和水平的博士和博士学位；(2)连续 来自项目领导、教师和同行的指导；(3)为所有学生提供翻译研究方面的培训。 这四位项目主任都是内科科学家，每个人都活跃在研究、研究生培训和 临床活动。学生会与董事们在招聘、研讨会、咨询、 课程，并不断改进。学生从医学培训的临床前阶段开始， 有一个为期3个学期的MSTP专业的综合分子医学(IMM)系列课程，由主任领导。IMM 向新学员介绍研究方法、科学写作、负责任的研究行为(RCR)、 严谨性、再现性和透明度(RRT)，以及隐性偏见。然后，学生通过临床见习继续学习。 在开始博士论文之前，在前沿课程中。博士导师的遴选是在与 项目负责人。对研究严谨性和博士导师的监督由MSTP的一名主任直接保证 每个论文委员会。完整的纵向临床经验跨越博士年限。在卫冕之后 博士论文，实习生进入医学培训的最后一年，其中包括指导临床和 翻译研究选修课(CTRE)，为MSTP学员定制。CTRE是为期6周的指导课程 拥有临床和研究两个方面，以及一个额外的医生-科学家教员导师。集成的 课程允许学生在7-8年内完成双学位培训，紧张程度之间的差距最小 研究活动和研究生培训。大多数学生的论文都是生物、化学、 人口科学或工程科学，还有其他人选择相关的研究项目，包括人类学、医学 病史和临床调查，这是一个与我们的临床翻译科学奖(CTSA)整合的项目。 其他活动培养计划的凝聚力，并包括RCR、RRT和Implative方面的持续培训 通过每周研讨会、我们的年度静修和年度研讨会以及定期的社交聚会来实现偏见。多样性 委员会由学生和教职员工共同领导，指导招聘和保留特殊人员的活动 实习生，包括一个新的暑期研究方案，面向未被充分代表的本科生，该方案将是 在授权期内实施。相关：受训者接受临床医学和医学方面的综合培训 并被授予医学博士和博士学位。通过一位创新的集成医生和科学家 课程，我们项目的不同毕业生正准备从事研究密集型职业， 严格的基础和转化性研究和临床护理。

PROJECT SUMMARY/ABSTRACT The Medical Scientist Training Program (MSTP) at the University of Wisconsin-Madison (UW-Madison) aims to train and prepare future leaders and physician-scientists in clinical medicine and biomedical research. Our program trains diverse students across numerous fields, with a curriculum and training plan that is continuously improved through metrics, critical self-assessment, and student input. Guiding principles of our program include: (1) a rigor and caliber of both MD and PhD training equivalent to single-degree candidates; (2) continuous mentoring from program leaders, faculty, and peers; and (3) training in translational research for all students. The four program directors are all physician-scientists and each is active in research, graduate training, and clinical activities. The student government works closely with the directors on recruitment, seminars, advising, curriculum, and continuous improvement. Students begin with the preclinical phase of medical training, along with a 3-semester MSTP-specific Integrated Molecular Medicine (IMM) course series, led by the directors. IMM introduces new trainees to research methodologies, scientific writing, responsible conduct of research (RCR), rigor, reproducibility and transparency (RRT), and implicit bias. Students then proceed through clinical clerkships in the ForWard curriculum before beginning the Ph.D. thesis. Ph.D. mentor selection is made in consultation with program leaders. Oversight of research rigor and Ph.D. mentorship is directly assured by an MSTP director on each thesis committee. An integrated Longitudinal Clinical Experience spans the Ph.D. years. After defending the Ph.D. thesis, trainees enter the final year of medical training, which includes the mentored Clinical & Translational Research Elective (CTRE), custom-designed for MSTP trainees. CTRE is a 6-week preceptorship with both clinical and research facets and an additional physician-scientist faculty mentor. The integrated curriculum allows students to complete dual degree training in 7-8 years, with a minimal gap between intense research activities and postgraduate training. A majority of student theses are in the biological, chemical, population or engineering sciences, yet others select allied programs of study including anthropology, medical history, and clinical investigation, a program integrated with our Clinical Translational Science Award (CTSA). Additional activities foster program cohesiveness and encompass continuous training in RCR, RRT and implicit bias via weekly seminars, our annual retreat and yearly symposium, and regular social gatherings. A diversity committee, jointly led by students and faculty, directs activities for recruitment and retention of exceptional trainees, including a new summer research program for underrepresented undergraduates, which will be implemented in the grant period. RELEVANCE: Trainees receive integrated training in clinical medicine and research and are awarded both M.D. and Ph.D. degrees. Through an innovative integrated physician-scientist curriculum, the diverse graduates of our program are poised for research-intensive careers that integrate rigorous basic and translational research and clinical care.