Open Science to Increase Reproducibility in Science

在研究的策略和设计中嵌入可重复性应被视为研究质量的一个关键前提。不幸的是，由于科学需要不断创新，出版压力，缺乏透明的报告，以及基于数量而不是质量的职业评估，只有一小部分已发表的研究可以复制。虽然在过去的十年中，针对资助者、出版商或个人研究人员引入了许多提高可重复性的干预措施，但只有少数经过了实证检验。这导致浪费了时间、精力和资源，而这些资源被投入到无效甚至有害的干预措施中。我们需要一种范式和文化的转变，从上到下和从下到上对研究与创新体系进行改革，以重新获得对科学的全面信任。开放科学以提高科学的可重复性（OSIRIS）旨在通过系统地收集有关潜在驱动因素的知识，测试有效的循证解决方案，确定利益相关者对可重复性的激励措施，并将可重复性嵌入研究设计来促进这一转变。我们着手开发和测试新的解决方案，同时也测试现有的解决方案，以提供指导，什么是可行的，什么是不可行的。这些目标将由一个独特的跨学科科学家团队实现，他们在开放科学（OS），可重复性，实施和数据共享方面具有实践专长，沿着一系列致力于利益相关者，包括早期职业研究人员，出版商和资助者，他们通过专门的共同创造活动密切参与该项目，并作为我们顾问委员会的一部分。到项目结束时，OSIRIS将提供和传播有关循证干预措施的指导，以提高科学的可重复性。

Embedding reproducibility in the strategy and design of research should be regarded as a key precondition to research quality. Unfortunately, only a fraction of published studies can be reproduced due to e.g, science’s need to be continuously innovative, pressure to publish, a lack of transparent reporting, and career assessments based on quantity rather than quality. While over the past decade many interventions to improve reproducibility have been introduced, targeted at funders, publishers, or individual researchers, only few of them have been empirically tested. This has resulted in a waste of time, effort, and resources invested in ineffective or even harmful interventions. We need a paradigm and culture shift to reform the R&I system both from the top down and the bottom up to regain overall trust in science. Open Science to Increase Reproducibility In Science (OSIRIS) aims to facilitate this shift by systematically gathering knowledge on the underlying drivers, testing effective evidence-based solutions, identifying incentives for reproducibility by stakeholders, and embedding reproducibility in research design. We set out to develop and test new solutions, while also testing existing solutions in order to provide guidance on what does and does not work. These aims will be realised by a unique, interdisciplinary team of scientists with hands-on expertise in Open Science (OS), reproducibility, implementation, and data sharing, along with a range of committed stakeholders, including early career researchers, publishers and funders, that are closely involved in the project through dedicated co-creation activities and as part of our advisory board. By the end of the project, OSIRIS will deliver and disseminate guidance about evidence based interventions that will improve the reproducibility of science.