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中文摘要
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项目总结 消化健康中心(DHC)行政核心的总体目标是发展和 实施整合了该中心主要职能的行政结构。核心目标是1) 实施整合中心主要职能的管理结构,2)发展接班人 确保DHC追求卓越和长期生存的计划,3)培养中心成员 由致力于消化疾病研究的创新研究人员提供,以及4)提高知名度和扩大规模 消化系统疾病研究。该中心的管理、日常运营和一般监督将是 领导委员会的职责,该委员会由中心主任、三名副主任、 和一名中心经理。领导人有独立的研究计划,并将互补的技能带给 委员会。每位副主任负责充实系列、临床部分、 或试点和可行性计划。他们每周开会,审查中心的运作情况。一年六到八次, 领导委员会的成员作为执行委员会开会,执行委员会也包括董事 生物医学核心和代表广大成员的两名DHC调查人员。的功能 执行委员会的职责是协助领导层审查核心利用情况,提供科学和 DHC的总体方向,并帮助解决因会员申请而产生的冲突。一年一次,或者 更多的时候,执行委员会与内部咨询委员会开会,审查 中心和维持机构支持,以促进消化系统疾病研究。这一运营结构具有 促进了由68名研究人员组成的研究基地之间的合作,他们在 过去4年,吸引了约3650万美元的直接资金用于消化系统疾病研究。浓缩物 计划促进更多的科学发展和成功的试点和可行性(P/F)计划 支持初级调查员的职业发展。监督DHC的战略运作是一项 由四位外部科学领袖组成的外部咨询委员会(EAB)。EAB正在进行评估 该中心的研究和规划方向,审查、确定和建议对 有价值的P/F应用,并评估行政和生物医学核心的有效性。这个 EAB准备并向儿科主席和研究主任提交年度报告 研究基金会,拥有中心的主要报告权和监督权。这个 在过去的14年里,DHC的行政核心结构和运作非常有效 存在,保持了DHC作为科学发现的真正催化剂,确保了 满足中心调查人员需求的最先进服务,已成功实施浓缩 和P/F计划,并培养了来自辛辛那提的非凡水平的参与和支持 儿童医院医疗中心将成为消化系统疾病有意义发现的真正催化剂。
英文摘要
PROJECT SUMMARY The overall goal of the Administrative Core of the Digestive Health Center (DHC) is to develop and implement an administrative structure that integrates key functions of the Center. The Core Aims are 1) to implement an administrative structure that integrates key functions of the Center, 2) to develop a succession plan that ensures the pursuit of excellence and long-term viability of the DHC, 3) to foster Center membership by innovative investigators committed to studies of digestive diseases, and 4) to increase visibility and expand digestive disease research. The Center management, day-to-day operation, and general oversight will be the responsibility of the Leadership Committee, which consists of the Center Director, three Associate Directors, and a Center Manager. The leaders have independent research programs and bring complementary skills to the Committee. Each Associate Director is responsible for either the Enrichment Series, Clinical Component, or Pilot and Feasibility Program. They meet weekly to review the operation of the Center. Six to 8 times a year, members of the Leadership Committee meet as an Executive Committee, which also includes the Directors of the Biomedical Cores and two DHC investigators representing the membership at large. The function of the Executive Committee is to assist the leadership in reviewing Core utilization, provide support with scientific and overall directions of the DHC, and help with conflicts arising from membership applications. Once a year, or more often, the Executive Committee meets with the Internal Advisory Board to review strategic needs of the Center and maintain institutional support to foster digestive disease research. This operational structure has promoted collaborations among our Research Base of 68 investigators, who have published 630 articles in the past 4 years and attracted ~$36.5 million in direct funds for digestive disease research. The Enrichment Program fosters additional scientific development and a successful Pilot and Feasibility (P/F) Program supports the career development of junior investigators. Overseeing the strategic operation of the DHC is an External Advisory Board (EAB) comprised of four extramural scientific leaders. The EAB evaluates ongoing research and programmatic directions of the Center, reviews, identifies, and recommends support for the most meritorious P/F applications, and assesses the effectiveness of the Administrative and Biomedical Cores. The EAB prepares and submits an annual report to the Chair of Pediatrics and Director Research of the Research Foundation, who holds the primary reporting authority and oversight of the Center. The Administrative Core structure and operation have been very effective over the past 14 years of the DHC existence, have maintained the DHC as a real catalyst of scientific discoveries, have ensured the delivery of state-of-the-art services that meet the needs of Center investigators, have implemented successful enrichment and P/F programs, and have fostered an exceptional level of engagement and support from Cincinnati Children’s Hospital Medical Center to be real catalysts of meaningful discoveries in digestive diseases.
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Biological Basis of Phenotypes and Clinical Outcomes in Biliary Atresia
  • 批准号:
    10824147
  • 项目类别:
  • 资助金额:
    $48.39万
  • 财政年份:
    2023
  • 负责人:
    JORGE A. BEZERRA
  • 依托单位:
Immunologic Dysfunction in Biliary Atresia
  • 批准号:
    8600672
  • 项目类别:
  • 资助金额:
    $40.79万
  • 财政年份:
    2013
  • 负责人:
    JORGE A. BEZERRA
  • 依托单位:
Immunologic Dysfunction in Biliary Atresia
  • 批准号:
    8435952
  • 项目类别:
  • 资助金额:
    $40.79万
  • 财政年份:
    2013
  • 负责人:
    JORGE A. BEZERRA
  • 依托单位:
Immunologic Dysfunction in Biliary Atresia
  • 批准号:
    8825487
  • 项目类别:
  • 资助金额:
    $40.79万
  • 财政年份:
    2013
  • 负责人:
    JORGE A. BEZERRA
  • 依托单位:
国内基金
海外基金
层出镰刀菌氮代谢调控因子AreA 介导伏马菌素 FB1 生物合成的作用机理
  • 批准号:
    2021JJ40433
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2021
  • 负责人:
    孙磊
  • 依托单位:
寄主诱导梢腐病菌AreA和CYP51基因沉默增强甘蔗抗病性机制解析
  • 批准号:
    32001603
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    24.0万元
  • 批准年份:
    2020
  • 负责人:
    段真珍
  • 依托单位:
AREA国际经济模型的移植.改进和应用
  • 批准号:
    18870435
  • 项目类别:
    面上项目
  • 资助金额:
    2.0万元
  • 批准年份:
    1988
  • 负责人:
    史树中
  • 依托单位: