Immunobiology of the Rheumatic Diseases

项目摘要/摘要 此次申报是对《风湿病免疫生物学》的竞争性更新 华盛顿大学医学院的培训计划。这个节目，它是 由约翰·阿特金森博士于1977年发起，在培训博士后研究员方面有着良好的记录 致力于风湿病研究的事业。培训计划的目标是 培养独立的科学家，最终致力于改善患者的预后 来自风湿病。当前的应用程序寻求对五个MD、MD/PHD或 每年的博士后实习生，结合了许多新的方案特征，以 加强这项训练任务。该计划从扩大的人才池中接受实习生 优秀申请者和与内科科学家培训密切关系的好处 医学和儿科课程，临床和翻译科学研究所， 以及生物学和生物医学科学部。这一竞争性续订的新功能是 提供临床/转化性研究轨道，以补充我们的基础科学研究 赛道。学员将从广泛的教学课程中受益，从而获得理科硕士学位 临床调查程度。这两条赛道的核心仍然是一位紧张的导师 研究经验。受训者由一位忠诚的初级教师导师指导， 与他们的奖学金监督委员会合作。35人的人才队伍资金雄厚 教师导师分为四个主题领域-免疫调节和宿主防御， 风湿病动物模型、临床/翻译研究和全基因组学。这些 教官是这笔赠款的主要力量。独一无二的协作环境 WUSM的教师队伍和教师队伍为专业发展提供了理想的环境 实习生的名单。在负责人中亲身实践研讨会、研究研讨会和计划 开展研究是对四个主题领域的补充。

PROJECT SUMMARY/ABSTRACT This application is the competitive renewal of the “Immunobiology of Rheumatic Diseases” Training Program at Washington University School of Medicine. The program, which was initiated in 1977 by Dr. John Atkinson, has a strong record of training postdoctoral fellows who are committed to careers in rheumatic disease research. The goal of the training program is to develop independent scientist who will ultimately work to improve outcomes of patients suffering from rheumatic diseases. The current application, which seeks support for five MD, MD/PhD, or PhD postdoctoral trainees per year, incorporates a number of new programmatic features to enhance this training mission. The Program accepts trainees from an expanded pool of outstanding applicants and benefits from close relationships to the Physician Scientist Training Programs in both Medicine and Pediatrics, the Institute of Clinical and Translational Sciences, and the Division of Biology and Biomedical Sciences. New to this competitive renewal is the offering of a clinical/translational research track which complements our basic science research track. Trainees will benefit from extensive didactic offerings leading to a Master of Science in Clinical Investigation degree. The centerpiece of either track remains an intense mentored research experience. Trainees are mentored by a committed primary faculty mentor, in collaboration with their scholarship oversight committee. The talented group of 35 well-funded faculty mentors are organized into four thematic areas- Immune Regulation and Host Defense, Animal Models of Rheumatic Disease, Clinical/Translational Research, and Omics. These preceptors are a major strength of this grant. The uniquely collaborative environment among the faculty preceptors and at WUSM provides an ideal setting for the professional development of the trainees. Hands on workshops, research seminars and programs in the Responsible Conduct of Research complement the four thematic areas.