Pediatric Infectious Diseases and Immunity Training Program

小儿传染病及免疫训练计划

• 批准号: 10187498
• 负责人: Anthony R French
• 金额: $ 16.1万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10187498
• 关键词: Childhood; Communicable Diseases; Immunity; Training Programs

PROJECT SUMMARY This application proposes the renewal of a post-doctoral training program in pediatric infectious diseases and immunology (PIDI-TP), based in the Divisions of Pediatric Infectious Diseases (ID) and Rheumatology at Washington University School of Medicine and St. Louis Children’s Hospital. The long-term objective is to train academic physician-scientists to carry out impactful research in pediatric infectious disease pathogenesis and host response. WUSM offers an outstanding training environment for physician-scientists, with nationally recognized hospitals conjoined with one of the nation’s premier biomedical research facilities. Many Washington University faculty members, both within and outside the Department of Pediatrics, are leading investigators in infectious diseases and human immunology. PIDI-TP will also take advantage of extensive WUSM facilities for genome sequencing and microbial genomics, as well as 100 other Research Cores. Our 35 PIDI-TP mentors, drawn from the Departments of Pediatrics, Medicine, Pathology/Immunology, and Molecular Microbiology, represent highly successful investigators with externally funded research programs and experience in mentoring physician- scientists. The PIDI-TP Program Director (PD) will be David Hunstad, MD, Associate Professor of Pediatrics and Chief of the Division of Pediatric ID. The co-PD will be Tony French, MD, PhD, Associate Professor of Pediatrics and Chief of the Division of Pediatric Rheumatology. These two PDs also direct the Pediatric Physician-Scientist Training Program (PSTP) at WUSM. Program activities and outcomes, trainee selection, and trainee progress will be overseen by an Executive Committee consisting of the two PDs and four other tenured investigators at WUSM who are heavily involved in physician-scientist training, and advised by external faculty who are nationally recognized experts in pediatric ID or immunology. Each trainee will be advised by an individualized Scholarship Oversight Committee (SOC), whose findings will be reviewed by the PDs and Executive Committee. The program will support two postdoctoral (MD or MD/PhD) trainees per year, to be recruited from pediatric fellowship programs in Infectious Diseases, Rheumatology, and Allergy/Immunology, as well as Neonatology, Pulmonary Medicine, Nephrology, and Critical Care, drawing in particular on MD/PhD trainees in our robust PSTP pipeline. Beyond the mentored research experience, educational and career development activities for trainees are organized in three arenas: Pathogens, Host, and Omics. A Core Curriculum for all participants will provide training in study design, biostatistics, human subjects research, animal use and care, scientific writing, preparation of grants, and genomics. Trainees will also receive extensive ongoing mentoring for career planning and to prepare for subspecialty Board examinations. Career development will be monitored by research mentors, the PDs, the Executive Committee, and the SOCs. Program evaluation will rely on short-term and long-term metrics as well as input from current and past trainees. Efforts are outlined to enhance diversity among trainees and mentors.

项目摘要 本申请建议更新儿科传染病博士后培训计划， 免疫学（PIDI-TP），基于儿科感染性疾病（ID）和流变学分部， 华盛顿大学医学院和圣路易斯儿童医院。长期目标是培养 学术医生-科学家在儿科感染性疾病发病机制和宿主方面开展有影响力的研究 反应WUSM为医生-科学家提供了出色的培训环境， 医院与国家最重要的生物医学研究设施之一相结合。许多华盛顿大学 儿科系内外的教职员工都是传染病领域的主要研究人员。 疾病和人类免疫学。PIDI-TP还将利用广泛的WUSM设施进行基因组测序。 测序和微生物基因组学，以及其他100个研究核心。我们的35名PIDI-TP导师来自 儿科，医学，病理/免疫学和分子微生物学部门，代表了高度 成功的研究者，有外部资助的研究项目和指导医生的经验， 科学家PIDI-TP项目主任（PD）将由儿科副教授、医学博士大卫亨斯塔德（David Hunstad）担任， 儿科ID部门的负责人。共同PD将是Tony French，医学博士，儿科副教授 和儿科风湿病科主任这两个PD还指导儿科医生-科学家 培训计划（PSTP）在WUSM。计划活动和成果、学员选择和学员进度将 由WUSM的两名PD和其他四名终身研究员组成的执行委员会监督 他们积极参与医生-科学家培训，并由国家级的外部教师提供咨询。 公认的儿科ID或免疫学专家。每位学员将获得个性化的奖学金 监督委员会（SOC），其调查结果将由PD和执行委员会审查。程序 每年将支持两名博士后（MD或MD/PhD）学员，从儿科奖学金计划中招募 在传染病，流变学，过敏/免疫学，以及新生儿，肺医学， 肾脏病学和重症监护，特别是在我们强大的PSTP管道中的MD/PhD学员。超出 为学员举办的研究经验、教育和职业发展活动分三个部分进行， 竞技场：病原体、宿主和组学。所有参与者的核心课程将提供研究设计培训， 生物统计学，人类受试者研究，动物使用和护理，科学写作，准备赠款和基因组学。 学员还将接受广泛的职业规划持续辅导，并为子专业委员会做准备 考试职业发展将由研究导师、PD、执行委员会、 和SOC。计划评估将依赖于短期和长期指标以及来自当前和 过去的实习生报告概述了为加强学员和导师之间的多样性所作的努力。