Pacific High Schools STEP-UP to One Health

项目总结 夏威夷大学约翰·A·伯恩斯医学院建议继续开发太平洋 加强计划，为代表不足和处境不利的高中提供研究、培训和指导 夏威夷以及美国和美国在太平洋的六个附属领土(E区)的学生。为 在过去的5年里，Pacific Step Up已经招收了104名学生参加NIDDK Step Up暑期项目，以及 在学年中让其他学生接触实验室科学。我们继续建设能力，以 在太平洋大学进行实验室研究，这是在我们之前没有的。我们追踪了375名升职校友 早在2005年就发现，大多数人都是以理科为重点接受大学教育的，许多人 还寻求研究生培训和期末学位。Pacific Step Up仍然是唯一正式的手- 关于美国太平洋地区高中的研究性培训计划，目前迫切需要建立和培育 寻求健康研究事业的人数不足的个人正在筹备中，以消除#年的健康差距 世界上这一地区。我们相信，太平洋加强行动已在该地区扎根，我们将 继续我们的研究、培训和指导计划，但在One的框架下绘制新的课程 健康。在研究培训、指导和能力建设方面的新战略和方法将进一步 NIDDK Step-Up通过使人们认识到 人类、动物和生态环境的健康；及其对与健康有关的问题的影响。我们的目标是 孕育和塑造一种重视健康研究作为解决相关健康问题的手段的文化 在这些社区中，并培养一批准备研究解决方案的“本土”科学家。正在做 因此，我们将完成NIDDK的使命，建立和多样化未来科学家感兴趣的管道 从跨部门和跨部门的多角度解决与NIDDK有关的健康和疾病问题 同一健康下的纪律处分方法。据此，我们提出了三个具体目标。(1)。招募最好的 来自美国太平洋地区七个州和地区的合格高中生(11年级和12年级)进入 加强暑期研究计划，并跟踪队列的学术进步，至少5 好几年了。(2)。提供个性化的研究经验(以及相关的教育和培训)，强调一个 卫生方法，以及与当地社区或人口的相关性。为升职校友提供后续行动，以及 专注于研究，指导延长9个月。(3)。同一健康在高校的萌芽和培养兴趣 同时加强地方大学的能力，使实验室、现场和社区能够 专注于一个健康概念的研究，所有这些都是为了支持太平洋逐步计划，通过扩大 应用人才库和研究机会，加强研究培训计划。

PROJECT SUMMARY The John A. Burns School of Medicine of the University of Hawaii proposes to continue to develop the Pacific STEP-UP Program to provide research training and mentoring to underrepresented and disadvantaged high school students in the State of Hawaii, and the six US and US affiliated territories in the Pacific (Region E). For the past 5 years, Pacific STEP-UP has enrolled 104 students in the NIDDK STEP-UP summer program, and exposed other students to laboratory sciences during the school year. We continued to build capacity for laboratory research in the Pacific colleges where there was none before us. We tracked 375 STEP-UP alumni from as early as 2005 to find that a majority pursued college education with a science emphasis, and many also sought post-graduate training and terminal degrees. Pacific STEP-UP remains the only formalized hands- on research training program for high schools in the US Pacific, amid the urgent need to build and foster a pipeline of underrepresented individuals seeking health research careers in order to combat health disparity in this region of the world. With confidence that Pacific STEP-UP has established roots in the region, we will continue our research training and mentoring program but charting a new course under framework of One Health. The new strategy and approach in research training, mentoring, and in capacity building will further NIDDK STEP-UP’s reach into the Pacific communities by bringing awareness of the interdependency of the well beings of humans, animals, and the eco-environment; and its impact on health-related issues. The goal is to seed and shape a culture that values One Health research as the means to address pertinent health issues in these communities, and grow a cadre of “home-grown” scientists readied to research for solutions. In doing so, we will fulfill NIDDK’s STEP-UP mission to build and diversify a pipeline of future scientists interested in tackling health and disease questions related to NIDDK from multiple angles of trans-sectorial and trans- disciplinary approach under One Health. Accordingly, we propose three Specific Aims. (1). Recruit best qualified high school students (11th and 12th grade) from the seven US State and Territories in the Pacific into the STEP-UP Summer Research Program, and track the cohort’s academic progress for a minimum of 5 years. (2). Provide individualized research experience (and related education and training) that stresses One Health approach, and local community or population relevance. Provide STEP-UP alumni with follow up, and research-focused, mentoring extending for 9 months. (3). Seed and nurture interests in One Health in high school students while strengthening local colleges’ capacity to enable laboratory-, field-, and community-based research with a focus on One Health concepts, all in support of the Pacific STEP-UP program by expanding application pool and research opportunities, and strengthening the research training program.