Racialization and Cardiovascular Risk Factors among Latinos - An Intersectional Approach

项目摘要/摘要 本次申请NHLBI K01教师多元化导师职业发展奖的目标是 为Deshira Wallace，MSPH，PhD，提供成为一名独立研究员的基本培训 心血管健康和影响少数族裔人群，特别是拉丁美洲黑人的健康不平等。Dr。 华莱士提出全面的研究建议和职业发展计划，将培训和 种族主义和交叉性、社会流行病学、心血管健康以及 先进的定量和定性方法。心血管疾病(CVD)在 居住在美国(美国)的拉丁裔。研究表明，心血管疾病的患病率因拉丁裔亚群而异， 而这些组内差异可能是由不同身份导致的不同暴露造成的。例如, 研究已经证实，拉美裔人在群体内的心血管疾病差异存在于原籍国、出生地和 在美国居住了几年。然而，根据拉美裔人的情况，对亚群分析的研究有限 在美国被种族主义，尽管拉丁裔同时体现了种族和民族(交叉性)。 种族主义是种族被个人理解并归因于个人的过程。要检查 拉美裔的种族主义经历，具体目的是：(1)探讨拉美裔黑人的种族主义经历 在美国；(2)构建一个多项目的种族主义变量；以及(3)比较心血管风险的轨迹 随着时间的推移，拉美裔人通过种族主义来评估差异的分数。目标1将使用深度访谈和 焦点小组，以了解个人和集体的信念和对影响黑人的因素的看法 拉美裔成年人在美国经历了种族主义。数据收集将在北卡罗来纳州进行。目标2(因素 分析)和AIM 3(混合模型)将使用波士顿波多黎各健康研究的数据。来补充 在拟议研究报告的范围内，该提案包括四个职业发展和培训目标： (一)深化对交叉性和民族化的理论认识，并将其应用于定性和 定量研究方法；(2)在潜在类和混合建模分析中培养定量技能 纵向流行病学数据；(3)整合社会科学和生物科学方法以解决病因 影响心血管健康的因素；以及(4)加强科学写作和写作技巧。这个 拟议的K01支持NHLBI专注于调查导致健康差异的因素 人口。拟议中的研究结果将通过跨部门的方法影响公众健康 提供有关种族主义经历及其对心血管健康影响的新信息 在拉美裔黑人中提供量身定制的预防和治疗战略。该项目将在 北卡罗来纳大学教堂山分校提供特殊的资源和指导，以培养博士。 华莱士执行拟议的K01；它还提供资源，以增加教师多样性，以成功 过渡为独立研究人员。

PROJECT SUMMARY/ABSTRACT The goal of this application for the NHLBI K01 Faculty Diversity Mentored Career Development award is to provide Deshira Wallace, MSPH, PhD, with the essential training to become an independent researcher in cardiovascular health and health inequities affecting minoritized populations, specifically Black Latinos. Dr. Wallace puts forth a comprehensive research proposal and career development plan integrating training in and application of theories of racialization and intersectionality, social epidemiology, cardiovascular health, and advanced quantitative and qualitative methods. Cardiovascular disease (CVD) is highly prevalent among Latinos living in the United States (US). Studies have shown that CVD prevalence varies by Latino subgroup, and these within-group disparities may be driven by different exposures due to varying identities. For example, studies have established that within-group CVD disparities exist for Latinos by country of origin, nativity, and years residing in the US. However, there is limited research on subgroup analysis according to how Latinos are racialized in the US, despite Latinos simultaneously embodying both a race and ethnicity (intersectionality). Racialization is the process by which race is understood by and ascribed to an individual. To examine the racialized experiences of Latinos, the specific aims are to (1) Explore racialization experiences of Black Latinos in the US; (2) Construct a multi-item racialization variable; and (3) Compare trajectories of cardiovascular risk scores over time among Latinos to assess differences by racialization. Aim 1 will use in-depth interviews and focus groups to understand individual and collective beliefs and perceptions of factors influencing how Black Latino adults experience racialization in the US. Data collection will occur in North Carolina. Aim 2 (factor analysis) and Aim 3 (mixture models) will use data from the Boston Puerto Rican Health Study. To complement the scope of the proposed research study, the proposal includes four career-development and training goals: (1) Deepen theoretical understanding of intersectionality and racialization and apply them to qualitative and quantitative research methods; (2) Develop quantitative skills in latent class and mixture modeling analysis of longitudinal, epidemiological data; (3) Integrate social and biological science approaches to address causal factors that influence cardiovascular health; and (4) Strengthen scientific writing and grantsmanship skills. The proposed K01 supports the NHLBI’s focus on investigating factors that account for differences in health among populations. Findings from the proposed research will impact public health by using an intersectional approach to provide novel information about experiences of racialization and their impact on cardiovascular health among Black Latinos to inform tailored prevention and treatment strategies. This project will be carried out at the University of North Carolina at Chapel Hill, which offers exceptional resources and mentoring to train Dr. Wallace to execute the proposed K01; it also provides resources to augment faculty diversity to successfully transition as an independent researcher.