课题基金 / 基金详情

Surgeon-Scientist Research Training in Injury Pathobiology and Outcomes In Critical Illness

Surgeon-Scientist Research Training in Injury Pathobiology and Outcomes In Critical Illness
外科医生科学家损伤病理学和危重疾病结果研究培训
批准号:
10555523
负责人:
PAUL C KUO
金额:
$8.42万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2023
资助国家:
美国
项目状态:
未结题
起止时间:
2023-07-01 至 2028-06-30

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中文摘要
翻译
项目总结/摘要 迫切需要通过培训下一代医生的基本知识和技能, 转化实验室和应用临床研究已得到广泛认可。越来越多的 然而,外科医生-科学家威胁着外科实践的未来发展。本次培训的总体目标 该计划旨在培养下一代外科医生科学家,他们拥有知识,技能和动力 进行相关的和有意义的研究,这将导致显着改善患者 结果。我们的培训计划寻求外科住院医师的申请, 研究培训以创伤病理学和危重病结局为中心,是一个广阔的研究竞技场 对所有外科专业都至关重要。每年,1名受训者,通常已完成3年手术 居住,将主要从一个庞大的人才库中招募, Morsani学院外科系的外科和综合血管外科住院医师项目 南佛罗里达大学医学院(USF)。我们的培训计划的中心枢纽是 DOS中的外科研究(DSR)。DSR经验丰富的调查人员,以及精心挑选的 来自USF其他5个部门的调查员将组成培训教师。培训学院由14名 致力于年轻外科医生的研究培训的个人,有一个既定的跟踪记录, 与创伤病理生物学和危重病结局的各个方面有关的校外资金,目前 作为主要研究者,拥有30多个NIH/VA奖项。我们的许多培训教师都是内科科学家, 为我们的学员提供医学和基础科学方面的重要经验和知识。基于 根据其他机构以往T32培训项目的PI/PD经验,我们建议 优化的培训计划,为学员提供密集的最先进的培训, 严格和可重复的研究,由个人发展计划指导。而学员将选择一个 他们选择的科学导师,所有学员将被要求制定书面研究建议和进展 报告,做正式的研究报告,参加研讨会,期刊俱乐部和教学课程 从事生物医学数据分析和负责任的研究工作。此外,学员还将获得 有机会获得健康信息学或医疗保健分析方面的其他研究生学位/认证。我们 有基础设施,资源,专业知识和动力,为我们的学员提供先进的, 在充满活力的科学环境中进行个性化的研究培训。我们相信,我们的培训计划将 最终为社会提供急需的外科医生-科学家,他们将处于临床实践的最前沿 在未来
英文摘要
Project Summary/Abstract The urgent need to refill the physician-scientist pipeline by training the next generation of physicians in basic and translational laboratory and applied clinical research has been widely recognized. A declining number of surgeon-scientists, however, threatens future advancement of surgical practice. The overall goal of this training program is to train the next generation of surgeon-scientists, who have the knowledge, skillsets and motivation to perform translationally relevant and meaningful research that will lead to significant improvements in patient outcomes. Our training program seeks applications from surgery residents interested in a 2-year full-time research training centered on injury pathobiology and outcomes in critical illness, a broad research arena essential for all surgical specialties. Each year, 1 trainee, who has typically completed 3 years of surgery residency, will be recruited primarily from a large pool of diverse and highly talented applicants for the general surgery and the integrated vascular surgery residency programs in the Department of Surgery, Morsani College of Medicine at University of South Florida (USF). The central hub of our training program is the Division of Surgical Research (DSR) in the DOS. Experienced investigators in the DSR, alongside carefully selected investigators from 5 other USF departments will form the training faculty. The training faculty is composed of 14 individuals who are committed to the research training of young surgeons, have an establish track record of extramural funding related to various aspects of injury pathobiology and outcomes in critical illness, and currently hold more than 30 NIH/VA awards as principal investigators. Many of our training faculty are physician scientists, which provides our trainees with critical experience and knowledge in both medical and basic sciences. Based on the experience of the MPI/PDs as PIs of previous T32 training programs at other institutions, we propose an optimized training plan to provide trainees with intensive state-of-the-art training in responsible conduct of rigorous and reproducible research that is guided by individual development plans. While trainees will select a scientific mentor of their choice, all trainees will be required to develop written research proposals and progress reports, to give formal research presentations, to participate in seminars, journal clubs and in didactic course work in biomedical data analysis and responsible conduct of research. In addition, trainees will have the opportunity to obtain additional graduate degrees/certifications in health informatics or health care analytics. We have the infrastructure, resources, expertise and motivation to provide our trainees with advanced and individualized research training in a vibrant scientific environment. We believe that our training program will ultimately provide the society with much needed surgeon-scientists, who will be at the forefront of clinical practice in the future.
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会议论文
Aptamer targeting of osteopontin in hepatocellular cancer
  • 批准号:
    8298389
  • 项目类别:
  • 资助金额:
    $19.51万
  • 财政年份:
    2012
  • 负责人:
    PAUL C KUO
  • 依托单位:
Aptamer targeting of osteopontin in hepatocellular cancer
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    8520257
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2012
  • 负责人:
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  • 依托单位:
Redox-mediated p300 regulation of hepatocyte NF-kB
  • 批准号:
    7090179
  • 项目类别:
  • 资助金额:
    $19.42万
  • 财政年份:
    2006
  • 负责人:
    PAUL C KUO
  • 依托单位:
Redox-mediated p300 regulation of hepatocyte NF-kB
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    7232456
  • 项目类别:
  • 资助金额:
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  • 财政年份:
    2006
  • 负责人:
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  • 依托单位:
国内基金
海外基金
Kidney injury molecular(KIM-1)介导肾小管上皮细胞自噬在糖尿病肾病肾间质纤维化中的作用
  • 批准号:
    81300605
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    23.0万元
  • 批准年份:
    2013
  • 负责人:
    唐琳
  • 依托单位: