Single Particle Elemental Analysis – Imaging Mass Cytometer Facility

该提案旨在建立一个澳大利亚设施，用于下一代高分辨率电感耦合等离子体飞行时间质谱（icpTOF-MS），以及高速激光消融（LA）成像。该设施是澳大利亚的第一个，将允许同时进行悬浮液或固体样品中单个颗粒和细胞的整个元素/同位素组成。当材料稀少或不易获得时，这一点尤其重要。预期成果包括在工业、生物、国防和环境研究部门产生新的知识和培训，并大大加强澳大利亚在纳米技术和元素成像方面的领导地位。

This proposal aims to establish an Australian facility for next generation high resolution inductively coupled plasma time-of-flight mass spectrometry (icpTOF-MS), coupled with high speed laser ablation (LA) imaging. The facility, being the first in Australia, will allow for the entire elemental/isotopic make-up of individual particles and cells in suspension, or within a solid sample, to be performed simultaneously. This is particularly significant when materials are rare, or not readily available. Expected outcomes include the generation of new knowledge and training in the industrial, biological, defence and environmental research sectors and the significant enhancement of Australia’s leadership in nanotechnology and elemental imaging.