Terahertz real-time release testing for pharmaceutical products

该项目将开发一种新的、快速的、非破坏性的测试仪器，用于预测片剂的功效和性能，其基础是使用太赫兹光直接测量片剂的孔隙率。通过这样做，我们希望有助于提高先进固体剂量药物的生产效率。我们的技术最初将作为一种测试方法销售，该测试方法可以与现有方法（溶出度/崩解时限和硬度测试）一起使用，以在设计过程中提高片剂质量。最终目标是在行业向连续制造发展的过程中，充当实时在线测试和反馈机制。

The project will develop a new, rapid and non-destructive test instrument for predicting tablet efficacy and performance, based on direct measurements of tablet porosity using terahertz light. In so doing, we expect to contribute to manufacturing efficiency improvements in production of advanced solid dose medicines. Our technology will initially be marketed as a test which can work alongside existing methods (dissolution/disintegration and hardness testing) to improve tablet quality during the design process. The ultimate goal is to act as a real-time, in-line test and feedback mechanism as the industry moves towards Continuous Manufacturing.