The roles of pathogen effectors in promoting rust diseases of plants

锈病威胁全球粮食安全。这个跨机构的项目旨在发现锈菌分泌的蛋白质在转移到植物细胞后如何促进疾病。它将利用亚麻和亚麻锈菌之间的相互作用作为一个强大的模型系统来验证这样的假设，即操纵宿主RNA代谢是支持锈病发病的基本机制。这项研究旨在极大地提高我们对锈菌用于建立侵染的分子机制的理解。所获得的知识有望通过确定可作为干预目标的致病过程，促进制定粮食作物锈病管理的新战略。

Rust diseases threaten global food security. This cross-institutional project aims to discover how proteins secreted by rust fungi promote disease following their translocation into plant cells. It will use the interaction between flax and the flax rust fungus as a powerful model system to test the hypothesis that manipulation of host RNA metabolism is a fundamental mechanism underpinning rust pathogenesis. This research is intended to dramatically improve our understanding of the molecular mechanisms used by rust fungi to establish infection. The knowledge gained is expected to facilitate the development of new strategies for rust disease management in food crops by identifying pathogenic processes that can be targeted for intervention.