DRUG ABUSE AND OTHER DEVIANT ADAPTATIONS TO STRESS

这是对ADAMHA Research的(竞争续订)请求 科学家奖(RSA)。广泛的目标包括研究， 职业提升和指导目标。研究的目标是 估计理论上知情的模型，这些模型指定(1) 药物滥用模式的心理社会前因和后果 以及其他对压力和结构的偏差适应 缓和这些关系，在一生中形成一个队列 在青春期早期和生命的第四个十年(35岁左右)之间， 和(2)世代之间的连续性和间断性( 一群人及其青春期子女)吸毒模式和 其他偏差适应，以及它们的相关性，在 两者处于相似的发育阶段(青春期早期) 几代人。第一组模型的数据来自家庭 采访了一群305岁左右的受试者，他们是 在20多岁到30岁之间(N=6,089)和之前接受采访 那是在七年级的时候。这些模型指定了直接和 早期生命阶段对后期阶段的间接影响并具体说明 缓和影响性质的情况。反常的 模式包括暴力、自毁行为、功能性 精神障碍，一系列犯罪活动，以及 违反有关收养和收养的规范性规定 传统社会角色的表现，以及 吸毒。这些模式被不同地建模为前置条件或 彼此之间的后果。其他前因后果 药物滥用和其他异常适应包括态度和 重要他人在不同社会环境中的行为反应 关系背景、慢性角色压力、归因于社会 身份、应对方式、生活事件、个人和 人际资源、同伴交往、自我感觉，以及 价值观。第二套模型的数据来自家庭 采访队列中已经到达的孩子 父母在青春期早期第一次接受采访时的年龄 或者当他们在研究过程中达到那个年龄的时候。这个 模型将考虑之间的连续性和不连续性 青春期早期的几代人通过特定的中介 影响，以及共同的先例经历。模特们将会是 在其他多变量技术中使用结构技术进行估计。 研究新方法将提高研究技能 多变量分析以及与其他公司员工的合作 纵向项目。指导活动包括指导 受雇于该项目和研讨会的研究生 在物质滥用的研究内容和方法上。

This is a (competing continuation) request for an ADAMHA Research Scientist Award (RSA). The broad objectives include research, career enhancement, and mentoring goals. The research objective is to estimate theoretically informed models that specify (1) the psychosocial antecedents and consequences of patterns of drug abuse and other deviant adaptations to stress and the constructs that moderate these relationships, for a cohort over the life span between early adolescence and the fourth decade of life (mid 30s), and (2) continuities and discontinuities across generations (the cohort and their adolescent children) of patterns of drug abuse and other deviant adaptations, and their correlates, observed at a comparable developmental stage (early adolescence) for the two generations. Data for the first set of models are from household interviews with a cohort of subjects in their mid 305 who were interviewed during their mid-to-late 20s (N=6,089) and, prior to that, during the seventh grade. The models specify direct and indirect effects of earlier life stages on later stages and specify the circumstances that moderate the nature of the effects. Deviant patterns include violence, self-destructive behaviors, functional psychiatric disorders, a range of criminal activities, and violation of normative prescriptions regarding the adoption and performance of conventional social roles, as well as patterns of drug abuse. These patterns are variously modeled as antecedents or consequences of each other. Other antecedents and consequences of drug abuse and other deviant adaptations include attitudes and behavioral responses of significant others in various social- relational contexts, chronic role strain, ascribed social identities, modes of coping, life events, personal and interpersonal resources, peer associations, self-feelings, and values. Data for the second set of models are from household interviews with the children of the cohort who have already reached the age the parent was when first interviewed in early adolescence or at the time they reach that age in the course of the study. The models will account for continuities and discontinuities between the generations during early adolescence by specifying mediating influences, and common antecedent experiences. The models will be estimated using structural among other multivariate techniques. Research skills will be enhanced by studying new methods of multivariate analysis and by collaboration with staffs of other longitudinal projects. Mentoring activities include guidance of graduate students who are employed on the project and in seminars in the substance and methods of research on substance abuse.