ELECTRON SPIN RESONANCE CENTER AT THE UNIV OF ILLINOIS

伊利诺伊州ESR研究中心成立于1985年10月，是一个 国家生物医学资源，其合作者在超过103个国家引用了它。 出版物在运作的头三年半。 的 IERC的目标是提供区域、国家和 国际生物医学研究界拥有独特而强大的 电子自旋领域的实验和理论能力 共振及相关技术。 IERC致力于实现这一目标， 重点是三个广泛的活动领域：（一）发展 最先进的仪器，以扩大实验的可能性范围 通过顺磁共振研究，（二）发展 新的方法论--即更强大的理论和实验 提高精密度、灵敏度和适用范围的方法 的共振技术，以及（iii）不断改善的IERC作为一个 资源提供生物医学界获得罚款 实验设施，专家工作人员咨询，特殊服务（如 作为ESR标准样品项目），以及最新信息，包括 中心开发的软件、硬件和仪器的修改， 研讨会，以及ESR研究和会议新闻（通过ESR中心 Newsletter）。 为了实现这些目标， 要求在未来五年内允许IERC提供五个 研究资源的组成部分：（1）技术研究和 开发，（2）合作研究，使用特殊设施， 方法，和IERC的专业知识，与区域，国家， 生物医学和相关科学的国际研究人员（3） 服务活动，（4）若干培训活动，包括一个新的 计划带来50个或更多的研究生或博士后学生超过 个性化培训计划的补助期;（5）传播 信息和技术。 IERC将开展的技术研究和开发活动 未来五年的重点是（1）发展， 完善的甚高频W波段ESR谱仪，第一个 其版本已经开始运行;（2）低频（S波段）ESE， 和相关技术的超精细光谱;（3）计算 支持电子自旋共振，（4）ESR成像的发展;（5） 低频（L波段）ESR波谱学的发展 仪器和技术。

The Illinois ESR Research Center, established in October of 1985, is a national biomedical resource whose collaborators have cited it in over 103 publications during the first three-and-a-half years of operation. The objective of the IERC is to provide the regional, national, and international biomedical research community with unique and powerful experimental and theoretical capabilities in the area of -Electron Spin Resonance and related techniques. The IERC works towards that objective by focussing on three broad areas of activity: (i) development of state-of- the-art instrumentation to extend the range of experimental possibilities available through paramagnetic resonance investigations, (ii) development of new methodology -- i.e. more powerful theoretical and experimental methods that enhance the precision, sensitivity, and scope of applicability of resonance techniques, and (iii) continual improvement of the IERC as a resource providing the biomedical community with access to fine experimental facilities, expert staff consultation, special services (such as the ESR standard sample project), and up-to-date information, including software developed by the Center, hardware and instrument modifications, workshops, and ESR research and conference news (through the ESR Centers Newsletter). In furtherance of these goals, continuing support is requested for the next five years to allow the IERC to provide the five components of a Research Resource: (1) technological research and development, (2) collaborative research, using the special facilities, methodologies, and expertise of the IERC, with regional, national, and international investigators in the biomedical and related sciences, (3) service activities, (4) several training activities, including a new program to bring in 50 or more graduate or postdoctoral students over the grant period for individualized training programs, and (5) dissemination of information and technology. The technological research and development activities on which IERC will concentrate over the next five-year period are (1) development and perfection of the very-high-frequency W-band ESR spectrometer, the first version of which has become operational; (2) low-frequency (S-band) ESE, and related techniques for hyperfine spectroscopy; (3) computational support for electron spin resonance, (4) ESR imaging developments; and (5) development of low-frequency (L-band in vivo) ESR spectroscopy instrumentation and techniques.