Expanding the toolbox of synthetic stealth polymers

本项目旨在开发具有先进生物医学性能的新一代合成仿生伪肽聚合物。这些聚合物将用于制造一系列纳米颗粒，这将允许研究结构、组成和表面功能化对其在生物环境中的行为的影响。仔细进行结构-物理化学性质关系和生物纳米相互作用的研究将在隐身和蛋白质驱避纳米材料领域产生新的知识。该项目的预期结果是产生一个生物惰性材料平台，该平台可能会在下一代纳米药物和医疗设备中找到作为构建模块的应用。

This project aims to develop a new generation of synthetic and biomimetic pseudo peptide polymers with advanced biomedical properties. The polymers will be used for the fabrication of a range of nanoparticles, which will allow to study the effect of architecture, composition and surface functionalisation on their behaviour in a biological environment. Carefully conducted structure-physicochemical property relationship and bio-nano interaction studies will generate new knowledge in the area of stealth and protein repellent nanomaterials. The intended outcome of the project is the generation of a platform of bioinert materials that could potentially find applications as building blocks in next generation nanomedicines and medical devices.