DESIGN OF PEDIATRIC COCHLEAR IMPLANTS

本项目的重点是多合同人工耳蜗的设计方面。 植入物专注于影响其能力的因素 取出并替换，可能是尺寸不同的植入物。这个 新设计必须将机械损伤和异物反应降至最低 在中耳和内耳结构中。预计这将是 包括表面材料、电极几何形状和 种植体固定技术与现有电极的比较 数组。评估将在非聋人动物模型中进行开发 孩子。决定使用非聋人模型是基于这样一个事实 毛细胞是耳蜗结构紊乱的敏感指标 和功能。此外，在植入电极阵列的聋人模型中， 诱发耳聋所致的耳蜗性损伤使 对植入物本身造成的损害的解释。

This project focuses on the design aspects of multicontract cochlear implants concentrating on the factors that affect their ability to be removed and replaced, possibly with dimensionally different implants. The new designs must cause minimal mechanical trauma and foreign body reaction in middle and inner ear structures. It is anticipated that this will include improvements in surface materials, electrode geometries and implant fixation techniques as compared with presently existing electrode arrays. Evaluation will be in non-deaf animal models of the developing child. The decision to use a non-deaf model is based on the fact that hair cells are sensitive indicators of disturbances of cochlear structure and function. Also, in deaf models with implanted electrode arrays, cochlear damage produced by inducing deafness complicates the interpretation of damage caused by the implant itself.