INNOVATIVE APPROACHES TO AGING AND CHEMOSENSORY SYSTEMS

请求提供支持，以加强关于 嗅觉与味觉(ISOT)将于7月7日至12日在加利福尼亚州圣地亚哥举行 1997年加入化学感受性科学协会年会 开会。国际嗅觉与味觉学术研讨会召开 每3-4年在世界上不同的地方。最后一个ISOT 将于1986年在美国举行。国家~S科学家， 临床医生和工业研究人员在感官衰老中的作用 嗅觉和味觉把美国会当成国家~S 传播他们的研究成果的主要论坛。这个 国际会议是介绍 在该领域的研究。在这次会议上提交的信息 迅速而广泛地传播到世界各地的化学传感 社区。衰老与脑功能显著减退有关 化学感官功能。阿尔茨海默病患者~S 尤其是嗅觉系统对 疾病的退化过程。此应用程序建议 通过邀请来自外部的专家来加强联合会议 化学感官是衰老领域的专家，新的 与老龄化研究有关的技术，以及在老龄化方面 化学传感功能参加座谈会带来的问题 将老龄化问题推到了前列。这些专家将推进科学研究 会议目标：1)鼓励使用创新的 技术，包括细胞和分子生物学技术 和神经成像将应用于老年人的衰老问题 化学传感系统，2)介绍在其他方面的研究进展 感官模式，以增强类似的潜力 化学感官方面的进展，3)化学感官科学家的最新进展 对化学感觉系统的老化进行研究，以刺激 针对老龄化问题的新的创新研究，以及4)促进 关于化学感官老化的教育。建议数 增强将产生对与年龄相关的更好的理解 化学感官损伤和刺激新的创新研究 到它的潜在机制。

Support is requested to enhance the International Symposium on Olfaction and Taste (ISOT) to be held in San Diego, CA, July 7-12 1997 as it joins the Association for Chemoreception Sciences Annual Meeting. An international symposium on Olfaction and taste is held every 3-4 years in a different location in the world. The last ISOT to be held in the U.S. was in 1986. The nation~s scientists, clinicians and industrial researchers in aging of the senses of olfaction and taste regard the American meeting as the nation~s major forum for dissemination of their research findings. The international meeting is the premier meeting for presentation of research in the field. Information presented at this meeting propagates rapidly and widely to the world-wide chemosensory community. Aging is associated with significant impairment in chemosensory function. Patients with Alzheimer~s disease exhibit particularly profound vulnerability of the olfactory system to the degenerative processes of the disease. This application proposes to enhance the joint meeting by inviting experts from outside the chemical senses who are experts in the area of aging, new technologies relevant to the study of aging, and in aging aspects of chemosensory function to participate in symposia which bring issues of aging to the forefront. These experts will advance the scientific objectives of the meeting by 1) encouraging the use of innovative technology, including cellular and molecular biological techniques and neuroimaging to be applied to the problem of aging of chemosensory systems, 2) presenting advances in research in other sensory modalities in order to enhance the potential for similar advances in the chemical senses, 3) updating chemosensory scientists with research in aging of chemosensory systems in order to stimulate new, innovative research directed at aging issues, and 4) fostering education in aging of the chemical senses. The proposed enhancement will produce better understanding of age-associated chemosensory impairment and stimulate new, innovative research into its underlying mechanisms.