Prototype development for sustained release amino acid supplement in horses

我们的项目目标是在一个新的领域应用微胶囊技术（基质颗粒技术或核壳胶囊化），为马开发一种功能性氨基酸β-丙氨酸的创新口服给药系统。这一创新将提高我们现有的β-丙氨酸产品STORM®的附加值。我们的目标是从马的消化道中实现持续的β-丙氨酸吸收，以维持和延长血液中的有益浓度，这反过来又将改善体内的保留（生物利用度），从而增强其生化功能和功效。我们将把新技术转移到一个新的领域：生产专业动物饲料。这项针对马优化的技术可以应用于其他单胃和反刍动物，为开发专业饲料成分和药物提供潜在应用，并在农业部门用于猪和肉牛，该项目的成功完成将使我们能够在市场上推广我们的“新改良”STORM产品，该产品具有更多的主要USP，具有增强功效和改善保质期/稳定性的强有力证据。这将极大地改善我们的国内销售，我们对那些我们已经建立分销商的国家的出口，并将加强对日本和印度等赛车行业蓬勃发展的新市场的扩张。我们的业务扩展导致这个项目与我们的两个商业技术合作伙伴将增加就业机会，特别是在农村地区，并将有助于英国的收支平衡。BHIC报告说，骑马现在在英国比橄榄球，钓鱼，或板球更受欢迎。我们的新产品代表了马运动营养的前沿进展，提供了对细节的关注，这对我们的马术队在伦敦2012年奥运会上取得成功并保持他们在全球舞台上的领先地位至关重要。

Our project objective is to apply microencapsulation technology (matrix particle techniques or core shell encapsulation) in a new sector to develop an innovative oral delivery system for a functional amino acid beta alanine for horses. This innovation will improve add value to our existing beta alanine product STORM®. We aim to achieve sustained beta alanine absorption from the horses’ digestive tract to maintain and prolong a beneficial concentration in the blood, which in turn will improve retention (bioavailability) in the body thus enhancing itsbiochemical functionality and efficacy. We will be transferring novel technology to a new area: production of specialist animal feeds.This technology optimised for use in horses can be applied for other monogastric andruminant animals offering potential applications for the development of specialist feedingredients and medicines and use in the agricultural sector for pigs and beef cattle, toimprove meat quality.Successful completion of the project will enable us to market our ‘New improved’ STORM product with further major USPs, with strong evidence of enhanced efficacy, and improved shelf life/stability. This will dramatically improve our domestic sales, our exports to those countries where in we have established distributors, and will enhance expansion into new markets with thriving racing industries such as Japan and India. Our business expansion resulting from this project in conjunction with our two business technology partners will increase jobs particularly in rural areas and will contribute to the UK’s balance of payments.The BHIC report that horse riding is now more popular in the UK than rugby, fishing, orcricket. Our new product represents a cutting edge advance in equine sports nutrition offering the attention to detail that is essential to build upon the success of our equestrian teams at the London 2012 Olympics and to keep them at the front of the global stage.