MASTERS PROGRAM IN PATIENT-ORIENTED RESEARCH

本申请申请资助由内外科医师学院(P和S)和哥伦比亚大学公共卫生学院(SPH)联合开发的为期两年的以患者为中心的教学硕士课程。该项目将由医学教授、GCRC项目主任亨利·金斯伯格和哥伦比亚大学欧文临床研究中心主任亨利·金斯伯格和生物统计学临床研究方法副教授兼硕士学位主任梅丽莎·贝格领导。这项提议的目标是开发一个强大的、多学科的教学培训计划，为年轻研究人员作为临床科学家的独立职业生涯做好准备。具体目标是：(1)开发以患者为中心的研究课程，获得公共卫生学院的硕士学位，为年轻研究人员开始临床调查职业生涯提供广泛的基础。(2)组建一个由活跃的临床研究科学家组成的顾问委员会，该委员会将建立和应用指导方针，以选择和评估年轻的研究人员作为硕士课程的学位候选人。(3)启动并维持一个长期的跟踪计划，以确定硕士计划对职业发展的影响。咨询委员会由P和S、SPH、口腔和口腔外科学院以及护理学院的高级临床研究人员组成。课程将以生物统计学和流行病学为中心，但将包括药理学、实验室方法、负责任的研究和资助机会等必修课。将有一系列持续的研究座谈会，其中将包括关于药物开发、FDA要求和专利问题的研讨会。所有学位候选人都将撰写一份NIH式的助学金，该助学金将由生物统计学部门的一名成员赞助，并由全校各系和各学校的高级调查人员指导。哥伦比亚大学及其主要附属机构--圣卢克斯·罗斯福医院中心和哈莱姆医院中心--的博士后研究员、讲师和助理教授的潜在申请者人数众多，而且才华横溢，许多由NIH资助的培训赠款和K奖已经到位。妇女和少数群体在申请者中有很好的代表性。公共卫生学院、内外科医生学院和长老会医院对拟议的计划做出了杰出的承诺，承诺每年向12名学生提供全额学费奖学金：这将确保每年都有优秀的申请者。

This application requests funding for a two-year, didactic Master's Program in Patient-Oriented Research that is being developed jointly by the College of Physicians and Surgeons (P and S) and the School of Public Health (SPH) of Columbia University. The program will be led by Henry Ginsberg, Professor of Medicine, Program Director of the GCRC, and Director of the Irving Center for Clinical Research at Columbia, and Melissa Begg, Associate Professor and Director of the Master's degree track in Clinical Research Methods in Biostatistics. The goal of this proposal is to develop a strong, multidisciplinary didactic training program that will prepare young investigators for independent careers as clinical scientists. The Specific Aims are: (1)To develop a curriculum in Patient-Oriented Research, leading to a Master's degree from the School of Public Health, that will provide a broad foundation for young investigators beginning their careers in clinical investigation. (2) To assemble an Advisory Board of active clinical research scientists that will establish and apply guidelines for the selection and evaluation of young investigators as degree candidates in the Master's program. (3) To initiate and maintain a long-term follow-up program to determine the impact of the Master's program on career development. An Advisory Board has been drawn from senior clinical investigators at P and S, SPH, the School of Dental and Oral Surgery, and the School of Nursing. The curriculum will be centered upon biostatistics and epidemiology, but will include required courses in pharmacology, laboratory methods, the responsible conduct of research and funding opportunities. There will be a continuing series of research colloquia which will include seminars on drug development, FDA requirements and patent issues. All degree candidates will write an NIH-style grant that will be sponsored by a member of the Division of Biostatistics and mentored by senior investigators from departments and schools Campus-wide. The potential applicant pool of postdoctoral fellows, Instructors, and Assistant Professors at Columbia and its major affiliates, the St. Lukes Roosevelt Hospital Center and the Harlem Hospital Center, is large and talented, with many NIH-funded training grants and K awards already in place. Women and minorities are very well represented in the applicant pool. The School of Public Health, the College of Physicians and Surgeons, and the Presbyterian Hospital have made an outstanding commitment to the proposed program by pledging to support twelve students each year with full tuition scholarships: this will ensure an outstanding applicant pool each year.