COORDINATION OF SITTING UP

由疾病引起的协调性轴向运动缺陷，例如 帕金森病，多发性硬化，小脑退化， 会导致福尔斯摔倒和受伤。 虽然这些赤字 关于轴向运动协调，我们所知甚少。 该项目将研究中枢神经系统如何 (CNS)通过使用“仰卧起坐”来协调轴向运动， 行为模型 中枢神经系统使用轴向运动协调的复杂模式来产生 导致坐起来的一系列动作。 这一系列 行动需要精确地调节时间和强度 肌肉活动在大量的主要肌肉群在一个 身体的大部分。 的顺序激活模式 肌肉暗示了本体感受输入在协调中的作用 坐起来。 神经学上正常的人类受试者将从仰卧起坐 位置 在仰卧起坐中，头部占体重的三分之二， 箱子必须被提起，由于这种重量分布， 坐起来不能作为一个同时运动的 整个上半身。 相反，它必须作为一系列 较小的身体升降机，从头部开始，向 的臀部 将使用各种机械干预来探索 肌肉活动模式与 运动的动力学和运动学 不同关节的运动 会受到限制，体重分布会改变 以不同的速度进行仰卧起坐。 的垂直力 将沿着记录在支撑表面上产生的 运动学和肌肉（EMG）活动。

Axial motor deficits in coordination caused by diseases, such as Parkinson disease, multiple sclerosis, and cerebellar degeneration, can contribute to falls and injuries. Although these deficits are common, relatively little is known about axial motor coordination. The proposed project will investigate how the central nervous system (CNS) coordinates axial movement by using the "sit-up" as a behavioral model. The CNS uses a complex pattern of axial motor coordination to produce the sequence of actions leading to sitting up. This sequence of actions requires precise regulation of the timing and intensity muscle activity in a large number of major muscle groups across a large part of the body. The sequential activation patterns of muscles suggests a role for proprioceptive input in the coordination of sitting up. Neurologically normal human subjects will sit up from a supine position. In sit-ups, two-thirds of the body weight in head and trunk must be lifted, and because of this weight distribution, sitting up cannot be accomplished as a simultaneous movement of the entire upper body. Instead, it must be performed as a sequence of smaller body lifts, beginning with the head and moving towards the hips. A variety of mechanical interventions will be used to explore the relationships between the patterns of muscle activity and the dynamics and kinematics of movement. Movement at different joints will be constrained, and the body weight distribution will be changed for sit-ups performed at different speeds. The vertical forces produced on the support surface will be recorded along with segmental kinematics and muscle (EMG) activity.