CORE--ANIMAL FACILITY

描述：(申请人描述)动物设施为研究所使用的所有研究动物提供护理，并确保合乎道德的使用。物种包括小鼠(转基因、基因敲除、突变、无菌裸体SCID和无菌品系)、大鼠、兔子和非洲爪哇。动物设施的工作人员按照首席调查员的指示，对动物进行几乎所有的程序，特别是那些在自然界中属于常规的程序。动物设施技术人员能够进行血液样本采集、注射、肿瘤接种、灌流、卵母细胞外科手术恢复、灌胃、尾部活组织检查和耳部切迹等程序。该机构保存研究所保存的所有转基因小鼠品系的系谱。这种集中的系统使调查员不必雇用和培训技术人员来执行这些例行程序和饲养任务，并产生了非常高效的服务。自1988年以来，该设施已获得美国实验动物护理认可协会(AAALAC)的认可。

Description: (Applicant's Description) The Animal Facility provides care for, and ensures the ethical use of, all research animals used at the Institute. Species include mice (transgenic, gene knockout, mutant, athymic nude Scid, and axenic strains), rats, rabbits, and Xenopus laevis. The Animal Facility staff conducts almost all procedures on animals, especially those that are routine in nature, following instructions of the principal investigator. Animal Facility technicians are able to perform procedures such as blood sample collection, injections, tumor inoculation, perfusions, surgical recovery of oocytes, gavaging, tail biopsies, and ear notching. The Facility maintains the pedigrees for all lines of transgenic mice held at the Institute. This centralized system frees the Investigator from having to hire and train technicians to perform these routine procedure and husbandry tasks, and results in a service that is very efficient. This facility has been accredited by the American Association for Accreditation of Laboratory Animal Care (AAALAC) since 1988.