PEDIATRIC NEPHROLOGY TRAINING

儿科肾脏病培训计划的目的 德克萨斯大学西南医学中心将培训儿科医生 作为学术儿科肾脏病的独立调查人员。 美国儿科肾科医生短缺， 儿科肾脏病的许多职位每年都有空缺。多数 儿科肾脏病的受训人员没有接受培训以使他们做好准备 从事独立研究的职业。这个应用程序申请两个人的资金 每年的儿科肾病研究员职位(临床培训为 由儿科部门支付)。研究员至少要花两个小时 在实验室工作多年，其兴趣包括：1)肾脏发育 生理学；2)信号转导；3)近端小管氯化钠的调节 转运；4)肾小管性酸中毒的发病机制；5)柠檬酸转运 6)近曲小管酸化的分子机制 和磷酸盐转运；7)肾移植中缺血的影响 排斥反应与巨噬细胞活化机制；8)热的作用 休克蛋白在急性肾衰竭中的作用；9)高血压的发病机制。 此外，研究员还参加由新闻部举办的每周会议。 儿科学旨在为学术医学的职业生涯做好准备。 涵盖的主题包括统计、计算机在生物医学中的使用 研究，如何写手稿和赠款，以及动物和动物的使用 研究中的人类。与医学和生物医学中的伦理相关的话题 在这些讲座和额外的医学研究中，研究是非常重要的 该大学还为研究员举办伦理讲座。联合周刊 儿科和内科肾脏科会议 包括临床和分子生物学杂志俱乐部，肾脏大赛， 肾脏研究会议和肾脏生理学系列讲座。研究员 还参加基础科学系的研讨会。实习生们密切地 由他们的研究导师和私人侦探监督，以确保 这一培训计划的目标已经实现。

The purpose of the training program in Pediatric Nephrology at the University of Texas Southwestern Medical Center is to train pediatricians for careers as independent investigators in academic Pediatric Nephrology. There is a shortage of Pediatric Nephrologists in the United States and many positions in Pediatric Nephrology go unfilled each year. Most trainees in Pediatric Nephrology do not receive training to prepare them for independent research careers. This application requests funds for two Pediatric Nephrology fellowship positions per year (clinical training is paid by the Department of Pediatrics). Fellows will spend at least two years in laboratories whose interests include: 1)renal developmental physiology; 2) signal transduction; 3) regulation of proximal tubule NaCl transport; 4) pathogenesis of renal tubular acidosis; 5) citrate transport and metabolism; 6) molecular mechanisms of proximal tubule acidification and phosphate transport; 7) the effect of ischemia in renal transplant rejection and the mechanism for macrophage activation; 8) role of heat shock proteins in acute renal failure; 9) pathogenesis of hypertension. In addition, fellows attend weekly conferences given by the Department of Pediatrics designed to prepare fellows for careers in academic medicine. Topics covered include statistics, use of Computers in biomedical research, how to write a manuscript and grant, and use of animals and humans in research. Topics related to ethics in medicine and biomedical research are strongly emphasized in these lectures and additional medical ethics lectures are also given by the University for fellows. Joint weekly conferences by the Divisions of Pediatric and Internal Medicine Nephrology include clinical and molecular biology journal clubs, renal grand rounds, renal research conference, and a renal physiology lecture series. Fellows also attend seminars in basic science departments. Trainees are closely supervised by their research mentor as well as the P.I. to insure that the goals of this training program are achieved.