CORE--CLINICAL

临床核心的目的是提供生物标本和 所有单个研究项目的行为数据。这个核心将 位于印第安纳波利斯。核心研究人员将招收和 保持中青年女性研究对象的队列 该中心为期五年，收集所有需要的生物样本 (泌尿生殖道拭子、宫颈分泌物、阴道冲洗、尿液、 宫颈活检和血液)、行为信息(自我管理 问卷和个人访谈)，并提供临时生殖 健康检查和数据收集，以促进受试者留存。 研究人员将包括研究协调员、研究护士 从业者，以及来自 马里恩县卫生局。研究护士将获得所有 生物标本。综合安全分队将履行两项重要的实地工作职能： (1)联系受试者的性伴侣以获取个人信息， 尿样，提供适当的抗生素治疗时，伴侣 受感染的妇女更愿意在马里恩县以外的地方接受治疗 诊所(钟花)；(2)每周与所有受试者接触 三个月的密集数据收集以获取尿样和 自我指导的阴道拭子、个人行为日记和访谈 信息。

The purpose of the Clinical Core is to provide biological specimens and behavioral data to all of the individual research projects. This core will be located in Indianapolis. Core research personnel will enroll and maintain the cohort of middle adolescent female research subjects over the five year duration of the center, collect all required biological samples (genitourinary swabs, endocervical secretions, vaginal lavages, urine, cervical biopsies, and blood), behavioral information (self-administered questionnaires and personal interviews), and provide interim reproductive health examinations and data collection to facilitate subject retention. Research personnel will include research coordinator, research nurse practitioner, and two Disease Intervention Specialists (DIS) from the Marion Country Health Department. The research nurse will obtain all biological specimens. DIS will perform two important fieldwork functions: (1) contact sexual partners of subjects to obtained personal information, urine samples, provide appropriate antibiotic treatment when partners of infected women prefer to be treated outside of the Marion County STD Clinic (Bell Flower); (2) weekly contact with all subjects during the three month period of intense data collection to obtain urine samples and self-directed vaginal swabs, personal behavioral diaries and interview information.