Fruit Integrative Modelling (FRIM)

商业水果生产面临着巨大的环境压力，气候变化加剧了环境压力，消费者对味道和营养价值的需求也发生了变化。因此，水果生物学的主要目标之一是了解影响成熟水果含量的因素，这些因素会影响水果的风味和质量。遗传因素和环境因素对果实品质都有很强的多方面影响。它们的行为和相互作用通常是如此复杂，以至于很难通过实验来研究它们的影响。有可能产生对环境条件做出反应的水果发育的实验派生模型，但这些模型本身并不能揭示不同番茄品种之间的遗传差异是如何影响结果的，这些差异对生化和细胞过程起作用。在不同的水平上，也可以建立果实内部新陈代谢的模型，预测番茄不同成分的形成速度，但这样的模型没有纳入环境影响对植物和水果的累积影响。这个项目的目的是将这两种建模方法结合起来，这样就可以预测特定遗传变异的果实在各种环境条件下的发育情况，从而合理地选择具有理想品质的番茄品系。

Commercial fruit production is under significant pressure from environmental stresses, exacerbated by climate change, but also from changes in the consumer's demand for taste and nutritional value. One of the key goals of fruit biology is therefore to understand the factors that influence the contents of the ripe fruit that influence flavour and quality. Both genetic and environmental factors have a strong and multifaceted influence on fruit quality. They usually act and interact in such a complex way that it is extremely difficult to study their effects experimentally. It is possible to generate experimentally-derived models of fruit development in response to environmental conditions, but such models alone do not reveal how the genetic variation between different tomato cultivars, which acts on biochemical and cellular processes, affects the outcome. At a different level, it is also possible to make models of the metabolism inside the developing fruit which can predict how fast different components of the tomato are being made, but such models do not incorporate the cumulative effects of the environmental influences on the plant and fruit. The aim of this project is to combine these two modelling approaches so that it is possible to predict how the fruit of particular genetic variants will develop under a variety of environmental conditions, and in that way to select rationally tomato strains with desirable qualities.