Control of early embryogenesis by extra-embryonic peptides

像动物一样，植物使用不对称的细胞分裂来创造模式和多样性。然而，植物如何指定和进行不对称分裂尚不清楚。这项建议侧重于揭示细胞间通讯作为推动植物受精卵不对称分裂的机制所起的作用。我们发现了一组在胚胎周围细胞中表达的多肽，它们调节受精卵的早期分裂。我们将利用这些发现来识别参与调控早期胚胎发育和模式的基因和蛋白质网络的新组件。通过这项工作，我们将揭示允许周围组织协调植物胚胎发育的分子过程。

Like animals, plants use asymmetric cell divisions to create pattern and diversity. However, how plants specify and carry out asymmetric divisions is not yet understood. This proposal focuses on uncovering the role of intercellular communication as a mechanism driving asymmetric division of the zygote in plants. We have uncovered a group of peptides expressed in embryo surrounding cells that regulate the early divisions of the zygote. We will use these findings to identify novel components to the network of genes and proteins that are involved in regulating early embryo development and patterning. Through this work we will uncover the molecular processes that allow surrounding tissues to coordinate the development of plant embryos.