PROSPECTIVE EVALUATION OF IMPLANT SUPPORTED BRIDGES

本研究的目的是比较和对比自然的反应， 刚性或非刚性地连接到骨结合的牙齿的基牙 植入物. 具有临床意义的标准，包括骨丢失和活动性 的牙齿和种植体将被用来评估这两个治疗 选择，以便随后帮助牙医选择方法， 种植体附着于自然牙列。 一个由三名口腔颌面外科医生组成的经验丰富的团队， 口腔修复医生和一名牙周病医生将被分配患者， 对牙齿和种植体的所有评价均为盲法， 由外科医生和修复师负责植入和修复。 此外，牙周病医生现在加入了团队，以评估 所有的病人。 一位统计学家参与了 并将作为合作研究者参与本研究。 将根据患者的双侧需要选择50名患者。 下颌骨远端延伸桥关节连接对一个完整的 上颌义齿 将一个10 mm长的Integral植入物放置在 右和左下颌第一磨牙区。 12周后， 种植体将用三个单元桥修复，自然基台 刚性或非刚性附着于种植体的牙齿评价。 在桥插入前后，X线片，软组织囊袋， 出血和菌斑指数、牙齿和种植体移动性以及一般 自植入之日起，每六个月评估一次临床质量 安置五年。 所有患者将在以下日期入组研究： 第三年年底。 将提交续期申请， 长期随访。 几位NIDR共识会议发言人要求NIH支持， 不同治疗方式的前瞻性研究 无牙患者 我们寻求有临床意义的信息。

The aim of this study is to compare and contrast the response of natural abutment teeth connected rigidly or non-rigidly to osseointegrated dental implants. Clinically significant criteria including bone loss and mobility of the teeth and implants will be used to evaluate these two treatment options, in order to subsequently aid the dentist in selecting methods of implant attachment to natural dentition. An experienced team of three Oral and Maxillofacial Surgeons, six Prosthodontists and one Periodontist will be assigned patients such that all evaluations of the teeth and implants are blinded, and not evaluated by the surgeon and prosthodontist who placed and restored the implants. In addition, the periodontist is now added to the team in order to evaluate all of the patients. A statistician has been involved with the design of this study and will participate as a co-investigator. Fifty patients will be selected based on their need for bilateral mandibular distal extension bridges articulating against a complete maxillary denture. One 10 mm. long Integral implant will be placed in the right and left mandibular first molar regions. Twelve weeks later, the implants will be restored with three unit bridges, with natural abutment teeth rigidly or non-rigidly attached to the implant evaluation. Prior to and following bridge insertion, radiographs, soft tissue pockets, bleeding and plaque indexes, tooth and implant mobility, and general clinical quality will be assessed every six months from the time of implant placement for five years. All patients will be entered into the study by the end of year three. A renewal application will be submitted to enable long term follow-up. Several NIDR consensus conference speakers requested NIH support for prospective studies on different treatment modalities for partially edentulous patients. We seek clinically significant information.