Exploitation of a novel fungicide for preventing fungal contamination and deterioration of products and materials

真菌由于其致病机理和对有价值的产品和材料的生物降解，给英国和全球带来了重大的社会和经济负担。为了应对后一个问题，预计到2020年，全球杀菌剂市场将达到106亿美元。然而，加强监管和对现有杀菌剂的抗药性正在推动对新技术的需求。诺丁汉大学BBSRC资助的一项新的受专利保护的杀菌剂技术利用了针对真菌蛋白质合成的一对制剂之间的协同作用。这种协同效应吸引了该行业，因为它降低了化学剂量和耐药性风险。我们最近与几家杀生剂公司的对话突出了这一领域需要我们解决的关键挑战(例如，聚合物中的功效，满足杀生剂法规)，以便他们能够追求他们对该技术的兴趣。这项提议的目的是为了实现这一目标，以确保与工业合作伙伴达成许可协议。

Fungi place major societal and economic burdens on the UK and globally, due to their pathogenesis and their biodeterioration of valuable products and materials. Countering the latter problem, the global biocide market is projected to reach $10.6 billion by 2020. However, tightening regulation and resistance to existing fungicides is driving a need for new technologies. A new, patent-protected fungicide technology arising from BBSRC-funded work at the University of Nottingham exploits synergies between pairs of agents that target fungal protein synthesis. This synergy is attracting the industry as it lowers the chemical dosages and risk of resistance. Our recent dialogue with several biocide companies has highlighted key challenges from this sector for us to address (e.g., efficacy within polymers, meeting biocide regulations), so they can pursue their interest in the technology. The aim of this proposal is to achieve that, in order to secure a licensing deal with an industrial partner.