Molecular engineering of high activity multifunctional biometallic catalysts for clickable chemistries

BioMetCat汇聚了一群独特的世界知名学者，开发了一种全新的方法，在充满活力和快速发展的“工业生物技术”领域为一系列行业(包括制药)制造高价值化学品。利用自然产生的细菌，这些细菌已经经过基因操纵，积累了纳米级的簇，具有强大的催化金属，再加上可以转化目标化学品的酶，我们将生产新型的“生物金属催化剂”，这可能会改变英国高价值化学品行业的战略领域。这项工作将基于生物学家、化学家和分析师的互补技能，使用生物学和物理科学的最新技术，并将开发新的解决方案，通过目前尚不存在的简单“一锅”工艺，将废金属流转化为广泛行业的高价值材料。

BioMetCat brings together a unique group of world-renowned academics to develop an entirely new approach tomaking high value chemicals for a range of industries (including pharmaceuticals), in the vibrant and rapidly developing area of "industrial biotechnology". Using naturally occurring bacteria, that have been genetically manipulated to accumulate nano-scale clusters of with powerful catalytic metals, alongside enzymes that can transform target chemicals, we will produce novel "biometallic catalysts" that can potentially transform strategic areas of the high value UK chemicals sector. The work will be based on complementary skills of biologists, chemists and analysts, using the latest techniques from biology and the physical sciences and will develop novel solutions, that can turn waste metal streams into high value materials for a wide range of industries via simple "one-pot" processes that are currently not available.