THE MECHANISM OF MESSENGER-RNA TRANSLATION

该项目将采用2种方法来描述初始步骤 使信使RNA参与信使RNA的正确起始 翻译. 首先，该项目将确定哪些核苷酸在 卫星烟草坏死病毒翻译起始位点周围 RNA（STNV RNA）是结合特异性起始因子所必需的 在信使RNA开始翻译之前。 二是这个 项目将探讨与吸收相关的一个或多个步骤 起始因子-STNV RNA复合物的核糖体结构参与的 翻译这个信使RNA。

This project will employ 2 approaches to characterize the initial steps that involve messenger-RNA in the correct initiation of messenger-RNA translation. First, this project will determine which nucleotides at and around the translation initiation site of satellite tobacco necrosis virus RNA (STNV RNA) are required for the binding of specific initiation factors prior to the initiation of translation of this messenger-RNA. Second, this project will explore the step or steps associated wih the uptake of initiation factor-STNV RNA complexes by ribosome structures involved in the translation of this messenger-RNA.