COMPUTER-ASSISTED ANALYSIS OF CHEMICAL SYNTHESIS

这项工作的主要目标是将数字计算机应用于 合成途径到复杂有机结构的派生。一个 拉萨通用问题解决程序(逻辑和启发式应用于 综合分析)，正在开发中，可由 用简单的图形输入输出结构式的化学家。这个 有机合成的原理和策略正在形式化以供使用 通过程序。包括远程搜索在内的各种策略 该计划正在使用各种能力。此外，广大的 关于合成化学的一系列信息正在被整理和 合理化，以提供丰富和有效的数据库。该程序可以是 适用于涉及生物重要物质和IS的问题 可供普遍使用的。

The major objective of this work is the application of digital computers to the derivation of synthetic pathways to complex organic structures. A general problem-solving program, LHASA (Logic and Heuristics Applied to Synthetic Analysis), is being developed which can be used interactively by a chemist with simple graphical input-output of structural formulas. The principles and strategies of organic synthesis are being formalized for use by the program. A variety of strategies including long-range search capabilities are being employed in the program. In addition, the vast range of information on synthetic chemistry is being organized and rationalized to provide a rich and effective database. The program can be applied to problems involving biologically important substances and is being made available for general use.